ADAM17 Gene Record

  • ADAM17 6868 Druggable Genome

    Alternate Names:

    6868
    ADAM METALLOPEPTIDASE DOMAIN 17
    ADAM17
    ADAM18
    CD156B
    CSVP
    NISBD
    NISBD1
    TACE
    603639
    195
    ENSG00000151694
    OTTHUMG00000090425
    ADAM 17 PRECURSOR (EC 3.4.24.86) (A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 17) (TNF-ALPHA CONVERTING ENZYME) (TNF-ALPHA CONVERTASE) (SNAKE VENOM-LIKE PROTEASE) (CD156B ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P78536]
    P78536
    TNF ALPHA CONVERTING ENZYME
    T82393

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Target Class Enzymes
    Target Subclass EC:3.4.24.86
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    CELL SURFACE
    NEUTRAL ZINC METALLOPEPTIDASE
    PROTEASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • ADERBASIB   ADAM17

    Interaction Score: 7.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • APRATASTAT   ADAM17

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • MARIMASTAT   ADAM17

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26192023


    Sources:
    DTC

  • CHEMBL599255   ADAM17

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000151694

    • Version: 101_38

    Alternate Names:
    ADAM17 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P78536

    • Version: January-2014

    Alternate Names:
    ADAM17 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.24.86

    Publications:

  • RussLampel: ENSG00000151694

    • Version: 26-July-2011

    Alternate Names:
    ADAM 17 PRECURSOR (EC 3.4.24.86) (A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 17) (TNF-ALPHA CONVERTING ENZYME) (TNF-ALPHA CONVERTASE) (SNAKE VENOM-LIKE PROTEASE) (CD156B ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P78536] Description
    ENSG00000151694 Ensembl Gene Id
    ADAM17 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: ADAM17

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Knapinska AM et al., 2015, SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes., J Med Chem

  • HingoraniCasas: ENSG00000151694

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000151694 Gene Symbol
    ADAM17 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: ADAM17

    • Version: 19.3

    Alternate Names:
    ENSG00000151694 Ensembl Gene ID
    CD156B Human Protein Atlas Gene Synonym
    cSVP Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER, CELL SURFACE, ENZYME

    Publications:

  • GO: ADAM17

    • Version: 01-February-2022

    Alternate Names:
    CSVP GO Gene Synonym
    TACE GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, NEUTRAL ZINC METALLOPEPTIDASE, PROTEASE

    Publications:

  • dGene: ADAM17

    • Version: 27-Jun-2013

    Alternate Names:
    6868 Gene ID
    ADAM18 dGene Synonym
    CD156B dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • TTD: TNF alpha converting enzyme

    • Version: 2020.06.01

    Alternate Names:
    ADAM17 TTD Gene Abbreviation
    T82393 TTD Target ID

    Gene Info:

    Publications: