134 |
ADENOSINE A1 RECEPTOR |
ADORA1 |
RDC7 |
102775 |
262 |
ENSG00000163485 |
OTTHUMG00000042125 |
P30542 |
AA1R_HUMAN |
ADENOSINE RECEPTOR A1 |
ADENOSINE A1 RECEPTOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P30542] |
PA24583 |
T92072 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR000276 |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Interpro Type | Family |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Uniprot Status | Swiss-Prot |
Target Main Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
Transmembrane Helix Count | 7 |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
agonist (activating) |
Novel drug target | Established target |
Trial Name | INO-8875 |
Mechanism of Interaction | Adenosine A1 receptor agonist |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Direct Interaction | yes |
Trial Name | rolofylline, MK-7418, KW-3902 |
partial agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor partial agonist |
Direct Interaction | yes |
partial agonist (activating) |
Trial Name | CVT-3619 |
Novel drug target | Established target |
Mechanism of Interaction | Adenosine A1 receptor partial agonist |
agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Trial Name | tecadenoson |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Trial Name | BG-9928 |
agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine A1 receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Adenosine A1 receptor agonist |
Direct Interaction | yes |
multitarget |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Adenosine receptor antagonist |
Trial Name | - |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | ADC4022, low-dose inhaled theophylline |
Novel drug target | Established target |
Mechanism of Interaction | Adenosine receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Adenosine receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | pentoxifylline, EHT0201 |
Novel drug target | Established target |
ADORA1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
P30542 | Uniprot Accession |
ADORA1 | Uniprot Gene Name |
AA1R_HUMAN | Uniprot Id |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | DRUGGABLE GENOME |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
ADENOSINE A1 RECEPTOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P30542] | Description |
ENSG00000163485 | Ensembl Gene Id |
ADORA1 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ADORA1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
P30542 | Uniprot Accession |
134 | Entrez Gene Id |
AA1R_HUMAN | Uniprot Id |
Target Main Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
PA24583 | PharmGKB ID |
ADORA1 | GENE_SYMBOL |
Adenosine receptor A1 | UNIPROT |
ENSG00000163485 | Gene Symbol |
ADORA1 | Ensembl Id |
DRUGGABLE GENOME |
134 | Gene ID |
RDC7 | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
ADORA1 | TTD Gene Abbreviation |
T92072 | TTD Target ID |
G PROTEIN COUPLED RECEPTOR |