240 |
ARACHIDONATE 5-LIPOXYGENASE |
ALOX5 |
5-LO |
5-LOX |
5LPG |
LOG5 |
152390 |
435 |
ENSG00000012779 |
OTTHUMG00000018081 |
P09917 |
ARACHIDONATE 5-LIPOXYGENASE (EC 1.13.11.34) (5-LIPOXYGENASE) (5-LO). [SOURCE:UNIPROT/SWISSPROT;ACC:P09917] |
5-lipoxygenase |
LOX5_HUMAN |
PA46 |
T00140 |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:1.13.11.34 |
Interpro Acc | IPR000907 |
Interpro Name | Lipoxygenase |
Uniprot Status | Swiss-Prot |
Interpro Short Name | LipOase |
Interpro Type | Family |
Uniprot Evidence | 1: Evidence at protein level |
Target Main Class | Enzymes |
Target Subclass | 1.13.11.34 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Trial Name | Zyflo |
Novel drug target | Established target |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
n/a |
Trial Name | VIA-2291 |
Novel drug target | Established target |
n/a |
Trial Name | licofelone, ML3000 |
Novel drug target | Established target |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Trial Name | balsalazide disodium,Colazal, Giazo |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Trial Name | MAX-002 |
Novel drug target | Established target |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Arachidonate 5-lipoxygenase inhibitor |
Direct Interaction | yes |
ALOX5 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ALOX5 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:1.13.11.34 |
P09917 | Uniprot Accession |
240 | Entrez Gene Id |
ENSG00000012779 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 1.13.11.34 |
ALOX5 | Display Id |
ARACHIDONATE 5-LIPOXYGENASE (EC 1.13.11.34) (5-LIPOXYGENASE) (5-LO). [SOURCE:UNIPROT/SWISSPROT;ACC:P09917] | Description |
ENSG00000012779 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
LOX5_HUMAN | Uniprot Id |
P09917 | Uniprot Accession |
ALOX5 | Uniprot Gene Name |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR000907 |
Interpro Name | Lipoxygenase |
DRUGGABLE GENOME |
5-LOX | TTD Gene Abbreviation |
T00140 | TTD Target ID |
LOG5 | GENE_SYMBOL |
ALOX5 | GENE_SYMBOL |
Arachidonate 5-lipoxygenase | UNIPROT |
ENSG00000012779 | Gene Symbol |
ALOX5 | Ensembl Id |
DRUGGABLE GENOME |
PA46 | PharmGKB ID |