CACNA1F Gene Record

  • CLEVIDIPINE   CACNA1F

    Interaction Score: 1.34

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes
    Trial Name Clevelox

    PMIDs:
    15492770


    Sources:
    TdgClinicalTrial ChemblInteractions

  • NIMODIPINE   CACNA1F

    Interaction Score: 0.9

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker

    PMIDs:
    20334460 20661350 19844625 20335610


    Sources:
    ChemblInteractions

  • AMLODIPINE MALEATE   CACNA1F

    Interaction Score: 0.67

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DILTIAZEM MALATE   CACNA1F

    Interaction Score: 0.67

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AMLODIPINE BESYLATE   CACNA1F

    Interaction Score: 0.54

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DILTIAZEM HYDROCHLORIDE   CACNA1F

    Interaction Score: 0.54

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AZD1305   CACNA1F

    Interaction Score: 0.45

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VERAPAMIL HYDROCHLORIDE   CACNA1F

    Interaction Score: 0.38

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ISRADIPINE   CACNA1F

    Interaction Score: 0.38

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ELPETRIGINE   CACNA1F

    Interaction Score: 0.34

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • NICARDIPINE HYDROCHLORIDE   CACNA1F

    Interaction Score: 0.3

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VERAPAMIL   CACNA1F

    Interaction Score: 0.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name Verapamil,Calan, Covera-HS
    Novel drug target Established target

    PMIDs:
    19125880


    Sources:
    TdgClinicalTrial TEND

  • FELODIPINE   CACNA1F

    Interaction Score: 0.21

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • NISOLDIPINE   CACNA1F

    Interaction Score: 0.18

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DRONEDARONE HYDROCHLORIDE   CACNA1F

    Interaction Score: 0.17

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • BEPRIDIL HYDROCHLORIDE   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ATAGABALIN   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PREGABALIN   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • IMAGABALIN   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN   CACNA1F

    Interaction Score: 0.1

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CELECOXIB   CACNA1F

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • NIFEDIPINE   CACNA1F

    Interaction Score: 0.06

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated L-type calcium channel blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000102001

    • Version: 101_38

    Alternate Names:
    CACNA1F Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: O60840

    • Version: January-2014

    Alternate Names:
    CACNA1F Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.A.1.11.11

    Publications:

  • TEND: O60840

    • Version: 01-August-2011

    Alternate Names:
    O60840 Uniprot Accession
    CAC1F_HUMAN Uniprot Id
    CACNA1F Gene Symbol

    Gene Info:
    Target Main Class Transporters
    Target Subclass Voltage_gated_ion_channels
    Target Subclass Channels

    Publications:

  • HopkinsGroom: O60840

    • Version: 11-September-2012

    Alternate Names:
    CAC1F_HUMAN Uniprot Id
    O60840 Uniprot Accession
    CACNA1F Uniprot Gene Name

    Gene Info:
    Interpro Short Name Ion_trans_dom
    Human Readable Name ION CHANNEL
    Interpro Type Domain

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000102001

    • Version: 26-July-2011

    Alternate Names:
    CACNA1F Display Id
    VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL ALPHA-1F SUBUNIT (VOLTAGE- GATED CALCIUM CHANNEL ALPHA SUBUNIT CAV1.4). [SOURCE:UNIPROT/SWISSPROT;ACC:O60840] Description
    ENSG00000102001 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • BaderLabGenes: CACNA1F

    • Version: February-2014

    Alternate Names:
    778 Entrez Gene ID

    Gene Info:
    Initial Gene Query Cav1.4
    Counted Citations from 1950-2000 97

    Gene Categories:
    ION CHANNEL

    Publications:

  • PharmGKB: CACNA1F

    • Version: 18-August-2020

    Alternate Names:
    PA26010 PharmGKB ID

    Gene Info:

    Publications:
    Ghodke-Puranik Y et al., 2013, Valproic acid pathway: pharmacokinetics and pharmacodynamics., Pharmacogenet Genomics
    Gong L et al., 2012, Celecoxib pathways: pharmacokinetics and pharmacodynamics., Pharmacogenet Genomics

  • ChemblInteractions: CACNAF1

    • Version: chembl_23

    Alternate Names:
    CACNAF1 GENE_SYMBOL
    CACNA1F GENE_SYMBOL
    Voltage-dependent L-type calcium channel subunit alpha-1F UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000102001

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000102001 Gene Symbol
    CACNA1F Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: CACNA1F

    • Version: 01-February-2022

    Alternate Names:
    Voltage-dependent L-type calcium channel subunit alpha-1F Gene Name
    O60840 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: