9254 |
CALCIUM VOLTAGE-GATED CHANNEL AUXILIARY SUBUNIT ALPHA2DELTA 2 |
CACNA2D2 |
CACNA2D |
607082 |
1400 |
ENSG00000007402 |
OTTHUMG00000156887 |
KIAA0558 |
Voltage-dependent calcium channel subunit alpha-2-2 |
Voltage-dependent calcium channel subunit delta-2 |
Voltage-gated calcium channel subunit alpha-2/delta-2 |
Voltage-dependent calcium channel subunit alpha-2/delta-2 |
Q9NY47 |
CA2D2_HUMAN |
PA26012 |
CALCIUM CHANNEL, VOLTAGE-DEPENDENT, ALPHA 2/DELTA SUBUNIT 2 ISOFORM B [SOURCE:REFSEQ_PEPTIDE;ACC:NP_006021] |
CASVDD |
Target Subclass | AuxillaryTransportUnit |
Transmembrane Helix Count | 1 |
Target Main Class | Transporters |
Target Subclass | CACNA2D |
Target Class | Transporters |
Target Subclass | TC:8.A.18.2.1 |
Human Readable Name | DRUGGABLE GENOME |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel alpha2/delta subunit 2 modulator |
Direct Interaction | yes |
inhibitor (inhibitory) |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
Trial Name | Depomed |
n/a |
Trial Name | budiodarone, ATI-2042 |
Novel drug target | Established target |
modulator |
Trial Name | XP13512 |
Novel drug target | Established target |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
n/a |
Trial Name | Safinamide |
Novel drug target | Established target |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Voltage-gated calcium channel blocker |
Direct Interaction | yes |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
CACNA2D2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
CACNA2D2 | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:8.A.18.2.1 |
CALCIUM CHANNEL, VOLTAGE-DEPENDENT, ALPHA 2/DELTA SUBUNIT 2 ISOFORM B [SOURCE:REFSEQ_PEPTIDE;ACC:NP_006021] | Description |
CACNA2D2 | Display Id |
ENSG00000007402 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
Q9NY47 | Uniprot Accession |
CACNA2D2 | Gene Symbol |
ENSG00000007402 | Ensembl Gene Id |
Target Subclass | AuxillaryTransportUnit |
Transmembrane Helix Count | 1 |
Target Main Class | Transporters |
PA26012 | PharmGKB ID |
CACNA2D2 | GENE_SYMBOL |
KIAA0558 | GENE_SYMBOL |
Voltage-dependent calcium channel subunit alpha-2/delta-2 | UNIPROT |
ENSG00000007402 | Gene Symbol |
CACNA2D2 | Ensembl Id |
DRUGGABLE GENOME |
CACNA2D2 | Gene Symbol |
ION CHANNEL |
Voltage-dependent calcium channel subunit alpha-2/delta-2 | Gene Name |
Q9NY47 | UniProt ID |
ION CHANNEL |