783 |
CALCIUM VOLTAGE-GATED CHANNEL AUXILIARY SUBUNIT BETA 2 |
CACNB2 |
CACNLB2 |
CAVB2 |
MYSB |
600003 |
1402 |
ENSG00000165995 |
OTTHUMG00000017764 |
Q08289 |
PA88 |
CACB2_HUMAN |
CAB2 |
Lambert-Eaton myasthenic syndrome antigen B |
Calcium channel voltage-dependent subunit beta 2 |
Voltage-dependent L-type calcium channel subunit beta-2 |
CACNAB2 |
CACNANB2 |
Target Main Class | Transporters |
Target Subclass | AuxillaryTransportUnit |
Target Subclass | TC:8.A.22.1.2 |
Target Class | Transporters |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Trial Name | felodipine ,Plendil |
Novel drug target | Established target |
Trial Name | enalapril + felodipine,Lexxel |
inhibitor (inhibitory) |
Trial Name | Tribenzor |
Novel drug target | Established target |
Trial Name | aliskiren + amlodipine,Tekamlo |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Verapamil,Calan, Covera-HS |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Voltage-gated calcium channel blocker |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Voltage-gated calcium channel modulator |
Direct Interaction | yes |
CACNB2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
CACNB2 | Gene Symbol |
CACNANB2 | Gene Symbol |
CACNAB2 | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:8.A.22.1.2 |
783 | Entrez Gene Id |
Q08289 | Uniprot Accession |
ENSG00000165995 | Ensembl Gene Id |
Target Main Class | Transporters |
Target Subclass | AuxillaryTransportUnit |
PA88 | PharmGKB ID |
ENSG00000165995 | Gene Symbol |
CACNB2 | Ensembl Id |
DRUGGABLE GENOME |
MYSB | GENE_SYMBOL |
CACNB2 | GENE_SYMBOL |
Voltage-dependent L-type calcium channel subunit beta-2 | UNIPROT |
Voltage-dependent L-type calcium channel subunit beta-2 | Gene Name |
Q08289 | UniProt ID |
ION CHANNEL |