DGIdb - CAMK2B Gene Record

CAMK2B 816 Druggable Genome

Alternate Names:

816
CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II BETA
CAMK2B
CAM2
CAMK2
CAMKB
607707
1461
ENSG00000058404
OTTHUMG00000023491
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II BETA CHAIN (EC 2.7.1.123) (CAM-KINASE II BETA CHAIN) (CAM KINASE II BETA SUBUNIT) (CAMK-II BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13554]
Q13554
KCC2B_HUMAN
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA
CaM-kinase II
T18299
CaMKIIbeta
MRD54

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Short Name	Ser/Thr_dual-sp_kinase_dom
Interpro Name	Serine/threonine- / dual-specificity protein kinase, catalytic domain
Interpro Type	Domain
Interpro Acc	IPR002290
Uniprot Evidence	1: Evidence at protein level
Uniprot Status	Swiss-Prot
Human Readable Name	KINASE
Gene Biotype	PROTEIN_CODING

(5 More Sources)

Gene Categories: Category Details

KINASE
SERINE THREONINE KINASE
DRUGGABLE GENOME
ENZYME

Publications:

Fan et al., 2005, G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II., J. Biol. Chem.
Pellicena P et al., 2014, CaMKII inhibitors: from research tools to therapeutic agents., Front Pharmacol
Condon et al., 2002, Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase., Endocrinology
Wright et al., 2004, A role for calcium/calmodulin kinase in insulin stimulated glucose transport., Life Sci.
Bassani et al., 1995, CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytes., Am. J. Physiol.
Valenzuela et al., 1998, Acute effects of ethanol on recombinant kainate receptors: lack of role of protein phosphorylation., Alcohol. Clin. Exp. Res.
Markoulaki et al., 2004, Fertilization stimulates long-lasting oscillations of CaMKII activity in mouse eggs., Dev. Biol.

RIMACALIB CAMK2B

Interaction Score: 6.51

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24600394

Sources:
TTD
IONOMYCIN CAMK2B

Interaction Score: 1.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15845548 12193581

Sources:
NCI
VASOPRESSIN CAMK2B

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15845548

Sources:
NCI
TRIFLUOPERAZINE CAMK2B

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15845548

Sources:
NCI
CAFFEINE CAMK2B

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7864197

Sources:
NCI
NIFEDIPINE CAMK2B

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14659970

Sources:
NCI
LY-2090314 CAMK2B

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALCOHOL CAMK2B

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9756045 15242787

Sources:
NCI
SNS-314 CAMK2B

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GSK-269962A CAMK2B

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEDIRANIB CAMK2B

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SOTRASTAURIN CAMK2B

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LINIFANIB CAMK2B

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SORAFENIB CAMK2B

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SP-600125 CAMK2B

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYC-116 CAMK2B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TAE-684 CAMK2B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ILORASERTIB CAMK2B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CENISERTIB CAMK2B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000058404
- Version: 101_38
Alternate Names:

CAMK2B Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000058404

Version: 26-July-2011

Alternate Names:

CAMK2B Display Id

ENSG00000058404 Ensembl Gene Id

CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II BETA CHAIN (EC 2.7.1.123) (CAM-KINASE II BETA CHAIN) (CAM KINASE II BETA SUBUNIT) (CAMK-II BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13554] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

HopkinsGroom: Q13554
- Version: 11-September-2012
Alternate Names:

Q13554 Uniprot Accession

KCC2B_HUMAN Uniprot Id

CAMK2B Uniprot Gene Name

Gene Info:

Interpro Short Name Ser/Thr_dual-sp_kinase_dom

Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

Human Readable Name DRUGGABLE GENOME

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:
TTD: CaM-kinase II
- Version: 2020.06.01
Alternate Names:

CAMK2 TTD Gene Abbreviation

T18299 TTD Target ID

Gene Info:

Publications:

Pellicena P et al., 2014, CaMKII inhibitors: from research tools to therapeutic agents., Front Pharmacol

NCI: CAMK2B

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Fan et al., 2005, G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II., J. Biol. Chem.

Markoulaki et al., 2004, Fertilization stimulates long-lasting oscillations of CaMKII activity in mouse eggs., Dev. Biol.

Valenzuela et al., 1998, Acute effects of ethanol on recombinant kainate receptors: lack of role of protein phosphorylation., Alcohol. Clin. Exp. Res.

HingoraniCasas: ENSG00000058404
- Version: 31-May-2017
Alternate Names:

ENSG00000058404 Gene Symbol

CAMK2B Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
dGene: CAMK2B
- Version: 27-Jun-2013
Alternate Names:

816 Gene ID

CAM2 dGene Synonym

CAMK2 dGene Synonym

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:
Pharos: CAMK2B
- Version: 01-February-2022
Alternate Names:

Calcium/calmodulin-dependent protein kinase type II subunit beta Gene Name

Q13554 UniProt ID

Gene Info:

Gene Categories:

KINASE, ENZYME

Publications:
DTC: CAMK2B
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

CAMK2B	Display Id
ENSG00000058404	Ensembl Gene Id
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II BETA CHAIN (EC 2.7.1.123) (CAM-KINASE II BETA CHAIN) (CAM KINASE II BETA SUBUNIT) (CAMK-II BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13554]	Description

Q13554	Uniprot Accession
KCC2B_HUMAN	Uniprot Id
CAMK2B	Uniprot Gene Name

Calcium/calmodulin-dependent protein kinase type II subunit beta	Gene Name
Q13554	UniProt ID

CAMK2B Gene Record

CAMK2B 816 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24600394

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15845548 12193581

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15845548

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15845548

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7864197

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14659970

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9756045 15242787

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
24600394

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
15845548 12193581

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15845548

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15845548

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7864197

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14659970

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9756045 15242787

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

CAMK2B Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

CAMK2B Display Id

ENSG00000058404 Ensembl Gene Id

CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II BETA CHAIN (EC 2.7.1.123) (CAM-KINASE II BETA CHAIN) (CAM KINASE II BETA SUBUNIT) (CAMK-II BETA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13554] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Q13554 Uniprot Accession

KCC2B_HUMAN Uniprot Id

CAMK2B Uniprot Gene Name

Gene Info:

Interpro Short Name Ser/Thr_dual-sp_kinase_dom

Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

Human Readable Name DRUGGABLE GENOME

Gene Categories:

KINASE, DRUGGABLE GENOME

Alternate Names:

CAMK2 TTD Gene Abbreviation

T18299 TTD Target ID

Publications:

Pellicena P et al., 2014, CaMKII inhibitors: from research tools to therapeutic agents., Front Pharmacol

Alternate Names:

ENSG00000058404 Gene Symbol

CAMK2B Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

816 Gene ID

CAM2 dGene Synonym

CAMK2 dGene Synonym

Gene Categories:

KINASE, SERINE THREONINE KINASE

Alternate Names:

Calcium/calmodulin-dependent protein kinase type II subunit beta Gene Name

Q13554 UniProt ID

Gene Categories:

KINASE, ENZYME