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CASP8 841 Druggable GenomeClinically Actionable
Alternate Names:
841 CASPASE 8 CASP8 ALPS2B CAP4 Casp-8 FLICE MACH MCH5 601763 1509 ENSG00000064012 OTTHUMG00000132821 Apoptotic cysteine protease Apoptotic protease Mch-5 Caspase-8 subunit p10 Caspase-8 subunit p18 FADD-homologous ICE/ced-3-like protease Caspase-8 FADD-like ICE ICE-like apoptotic protease 5 MORT1-associated ced-3 homolog CASPASE-8 PRECURSOR (EC 3.4.22.-) (CASP-8) (ICE-LIKE APOPTOTIC PROTEASE 5) (MORT1-ASSOCIATED CED-3 HOMOLOG) (MACH) (FADD-HOMOLOGOUS ICE/CED-3-LIKE PROTEASE) (FADD-LIKE ICE) (FLICE) (APOPTOTIC CYSTEINE PROTEASE) (APOPTOTIC PROTEASE MCH-5) (CAP4). [SOURCE:U Q14790 CASP8_HUMAN 761 Gene Info:
Human Readable Name DRUGGABLE GENOME Human Readable Name PROTEASE Interpro Short Name Pept_C14_p45 Interpro Acc IPR002398 Interpro Type Family Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Name Peptidase C14, caspase precursor p45 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
PROTEASE DRUGGABLE GENOME CLINICALLY ACTIONABLE ENZYME Publications:
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Interaction Score: 6.18
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Interaction Score: 4.95
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Caspase-8 inhibitor -
Interaction Score: 1.55
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Caspase inhibitor Direct Interaction yes
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- Version: 101_38
Alternate Names:
CASP8 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
Q14790 Uniprot Accession CASP8_HUMAN Uniprot Id CASP8 Uniprot Gene Name Gene Info:
Interpro Short Name Pept_C14_p45 Interpro Acc IPR002398 Interpro Type Family Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
CASPASE-8 PRECURSOR (EC 3.4.22.-) (CASP-8) (ICE-LIKE APOPTOTIC PROTEASE 5) (MORT1-ASSOCIATED CED-3 HOMOLOG) (MACH) (FADD-HOMOLOGOUS ICE/CED-3-LIKE PROTEASE) (FADD-LIKE ICE) (FLICE) (APOPTOTIC CYSTEINE PROTEASE) (APOPTOTIC PROTEASE MCH-5) (CAP4). [SOURCE:U Description ENSG00000064012 Ensembl Gene Id CASP8 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
841 Entrez Gene ID 761 CIViC Gene ID Gene Info:
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Alternate Names:
Gene Info:
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- Version: chembl_23
Alternate Names:
MCH5 GENE_SYMBOL CASP8 GENE_SYMBOL Caspase-8 UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000064012 Gene Symbol CASP8 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 19.3
Alternate Names:
ENSG00000064012 Ensembl Gene ID Casp-8 Human Protein Atlas Gene Synonym FLICE Human Protein Atlas Gene Synonym Gene Info:
Gene Categories:
ENZYME Publications:
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Alternate Names:
MCH5 GO Gene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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Alternate Names:
CASP8 Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
841 Gene ID ALPS2B dGene Synonym CAP4 dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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Alternate Names:
Caspase-8 Gene Name Q14790 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 04-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: