• CD33 945 Druggable Genome

    Alternate Names:

    945
    CD33 MOLECULE
    CD33
    SIGLEC-3
    SIGLEC3
    p67
    159590
    1659
    ENSG00000105383
    OTTHUMG00000182891
    CD33_HUMAN
    P20138
    Myeloid cell surface antigen CD33
    Sialic acid-binding Ig-like lectin 3
    gp67
    CD_antigen=CD33
    PA26210
    T38950

    Gene Info:

    Target Subclass StructuralAndAdhesion
    Target Subclass IG_AdhesionProteins
    Transmembrane Helix Count 1
    Target Main Class Other
    Target Class Miscellaneous
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 20.61

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Trial Name lintuzumab, SGN-33
    Novel drug target Established target
    Mechanism of Interaction Myeloid cell surface antigen CD33 other

    PMIDs:
    None found


  • Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Myeloid cell surface antigen CD33 binding agent
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Myeloid cell surface antigen CD33 other

    PMIDs:
    None found


  • Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Myeloid cell surface antigen CD33 binding agent
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CD33 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    CD33 Gene Symbol
    P20138 Uniprot Accession
    CD33_HUMAN Uniprot Id

    Gene Info:
    Target Subclass StructuralAndAdhesion
    Target Subclass IG_AdhesionProteins
    Transmembrane Helix Count 1

    Publications:

    • Version: January-2014

    Alternate Names:
    CD33 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass StructuralAndAdhesion
    Target Subclass IG_AdhesionProteins

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000105383 Gene Symbol
    CD33 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    SIGLEC3 GENE_SYMBOL
    CD33 GENE_SYMBOL
    Myeloid cell surface antigen CD33 UNIPROT

    Gene Info:

    Publications:

    • Version: 18-August-2020

    Alternate Names:
    PA26210 PharmGKB ID

    Gene Info:

    Publications:

  • GO: CD33

    • Version: 01-February-2022

    Alternate Names:
    SIGLEC3 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CD33 TTD Gene Abbreviation
    T38950 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-February-2022

    Alternate Names:
    Myeloid cell surface antigen CD33 Gene Name
    P20138 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: