DGIdb - CD5 Gene Record

CD5 921 Druggable Genome

Alternate Names:

921
CD5 MOLECULE
CD5
LEU1
T1
153340
1685
ENSG00000110448
OTTHUMG00000167825
P06127
CD5_HUMAN
Lymphocyte antigen T1/Leu-1
T-cell surface glycoprotein CD5
CD_antigen=CD5
T-CELL SURFACE GLYCOPROTEIN CD5 PRECURSOR (LYMPHOCYTE GLYCOPROTEIN T1/LEU-1) (LYMPHOCYTE ANTIGEN CD5). [SOURCE:UNIPROT/SWISSPROT;ACC:P06127]

Gene Info:

Interpro Short Name	Srcr_rcpt
Interpro Name	Speract/scavenger receptor
Uniprot Evidence	1: Evidence at protein level
Uniprot Status	Swiss-Prot
Interpro Type	Domain
Interpro Acc	IPR001190
Human Readable Name	DRUGGABLE GENOME
Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME

Publications:

Alberola-Ila et al., 1992, Intracellular events involved in CD5-induced human T cell activation and proliferation., J. Immunol.
Teutsch et al., 1995, Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin., Int. Immunol.
Savion et al., 1999, A possible role for granulocyte macrophage-colony stimulating factor in modulating teratogen-induced effects., Teratog., Carcinog. Mutagen.

ZOLIMOMAB ARITOX CD5

Interaction Score: 15.46

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction T-cell surface glycoprotein CD5 binding agent

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
IONOMYCIN CD5

Interaction Score: 3.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7540861

Sources:
NCI
INOSITOL CD5

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1371522

Sources:
NCI
REGRAMOSTIM CD5

Interaction Score: 2.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10379842

Sources:
NCI

Ensembl: ENSG00000110448
- Version: 101_38
Alternate Names:

CD5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P06127
- Version: 11-September-2012
Alternate Names:

CD5 Uniprot Gene Name

921 Entrez Gene Id

CD5_HUMAN Uniprot Id

Gene Info:

Interpro Short Name Srcr_rcpt

Interpro Name Speract/scavenger receptor

Uniprot Evidence 1: Evidence at protein level

Gene Categories:

DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000110448

Version: 26-July-2011

Alternate Names:

ENSG00000110448 Ensembl Gene Id

CD5 Display Id

T-CELL SURFACE GLYCOPROTEIN CD5 PRECURSOR (LYMPHOCYTE GLYCOPROTEIN T1/LEU-1) (LYMPHOCYTE ANTIGEN CD5). [SOURCE:UNIPROT/SWISSPROT;ACC:P06127] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

NCI: CD5

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Alberola-Ila et al., 1992, Intracellular events involved in CD5-induced human T cell activation and proliferation., J. Immunol.

Teutsch et al., 1995, Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin., Int. Immunol.

Gignac et al., 1990, Down-regulation of CD5 mRNA in B-chronic lymphocytic leukemia cells by differentiation-inducing agents., Eur. J. Immunol.

HingoraniCasas: ENSG00000110448
- Version: 31-May-2017
Alternate Names:

ENSG00000110448 Gene Symbol

CD5 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
ChemblInteractions: LEU1
- Version: chembl_23
Alternate Names:

LEU1 GENE_SYMBOL

CD5 GENE_SYMBOL

T-cell surface glycoprotein CD5 UNIPROT

Gene Info:

Publications:
GO: CD5
- Version: 01-February-2022
Alternate Names:

LEU1 GO Gene Synonym

Gene Info:

Gene Categories:

EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

Mechanism of Interaction	T-cell surface glycoprotein CD5 binding agent
Direct Interaction	yes

ENSG00000110448	Ensembl Gene Id
CD5	Display Id
T-CELL SURFACE GLYCOPROTEIN CD5 PRECURSOR (LYMPHOCYTE GLYCOPROTEIN T1/LEU-1) (LYMPHOCYTE ANTIGEN CD5). [SOURCE:UNIPROT/SWISSPROT;ACC:P06127]	Description

LEU1	GENE_SYMBOL
CD5	GENE_SYMBOL
T-cell surface glycoprotein CD5	UNIPROT

CD5 Gene Record

CD5 921 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

ZOLIMOMAB ARITOX CD5

Interaction Types & Directionality: n/a

Interaction Info: Mechanism of Interaction T-cell surface glycoprotein CD5 binding agent Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

IONOMYCIN CD5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7540861

Sources: NCI

INOSITOL CD5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1371522

Sources: NCI

REGRAMOSTIM CD5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10379842

Sources: NCI

Ensembl: ENSG00000110448

Alternate Names: CD5 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P06127

Alternate Names: CD5 Uniprot Gene Name 921 Entrez Gene Id CD5_HUMAN Uniprot Id

Gene Info: Interpro Short Name Srcr_rcpt Interpro Name Speract/scavenger receptor Uniprot Evidence 1: Evidence at protein level

Gene Categories: DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000110448

Alternate Names: ENSG00000110448 Ensembl Gene Id CD5 Display Id T-CELL SURFACE GLYCOPROTEIN CD5 PRECURSOR (LYMPHOCYTE GLYCOPROTEIN T1/LEU-1) (LYMPHOCYTE ANTIGEN CD5). [SOURCE:UNIPROT/SWISSPROT;ACC:P06127] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

NCI: CD5

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000110448

Alternate Names: ENSG00000110448 Gene Symbol CD5 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

ChemblInteractions: LEU1

Alternate Names: LEU1 GENE_SYMBOL CD5 GENE_SYMBOL T-cell surface glycoprotein CD5 UNIPROT

Gene Info:

Publications:

GO: CD5

Alternate Names: LEU1 GO Gene Synonym

Gene Info:

Gene Categories: EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction T-cell surface glycoprotein CD5 binding agent

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
7540861

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1371522

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10379842

Sources:
NCI

Alternate Names:

CD5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

CD5 Uniprot Gene Name

921 Entrez Gene Id

CD5_HUMAN Uniprot Id

Gene Info:

Interpro Short Name Srcr_rcpt

Interpro Name Speract/scavenger receptor

Uniprot Evidence 1: Evidence at protein level

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000110448 Ensembl Gene Id

CD5 Display Id

T-CELL SURFACE GLYCOPROTEIN CD5 PRECURSOR (LYMPHOCYTE GLYCOPROTEIN T1/LEU-1) (LYMPHOCYTE ANTIGEN CD5). [SOURCE:UNIPROT/SWISSPROT;ACC:P06127] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000110448 Gene Symbol

CD5 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

LEU1 GENE_SYMBOL

CD5 GENE_SYMBOL

T-cell surface glycoprotein CD5 UNIPROT

Alternate Names:

LEU1 GO Gene Synonym

Gene Categories:

EXTERNAL SIDE OF PLASMA MEMBRANE