CHRNA1 Gene Record

  • CHRNA1 1134 Druggable Genome

    Alternate Names:

    1134
    CHOLINERGIC RECEPTOR NICOTINIC ALPHA 1 SUBUNIT
    CHRNA1
    ACHRA
    ACHRD
    CHRNA
    CMS1A
    CMS1B
    CMS2A
    FCCMS
    SCCMS
    100690
    1955
    ENSG00000138435
    OTTHUMG00000132357
    P02708
    ACHA_HUMAN
    ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA
    CHNRA
    ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P02708]
    PA26487
    Neuronal acetylcholine receptor alpha-1
    T04689

    Gene Info:

    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Short Name Neur_chan_lig-bd
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL
    Interpro Acc IPR006201
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Interpro Short Name Neur_channel
    Uniprot Status Swiss-Prot
    Interpro Acc IPR006202
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • DECAMETHONIUM   CHRNA1

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DECAMETHONIUM BROMIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor partial agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PIPECURONIUM BROMIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SUCCINYLCHOLINE CHLORIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VECURONIUM BROMIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • TUBOCURARINE CHLORIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • RAPACURONIUM BROMIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • METOCURINE IODIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DOXACURIUM CHLORIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIVACURIUM CHLORIDE   CHRNA1

    Interaction Score: 0.82

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PANCURONIUM BROMIDE   CHRNA1

    Interaction Score: 0.69

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ROCURONIUM BROMIDE   CHRNA1

    Interaction Score: 0.69

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ATRACURIUM BESYLATE   CHRNA1

    Interaction Score: 0.69

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CISATRACURIUM BESYLATE   CHRNA1

    Interaction Score: 0.69

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GALLAMINE TRIETHIODIDE   CHRNA1

    Interaction Score: 0.59

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000138435

    • Version: 101_38

    Alternate Names:
    CHRNA1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P02708

    • Version: 11-September-2012

    Alternate Names:
    CHRNA1 Uniprot Gene Name
    ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA Uniprot Protein Name
    P02708 Uniprot Accession

    Gene Info:
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Short Name Neur_chan_lig-bd
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000138435

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000138435 Ensembl Gene Id
    ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P02708] Description
    CHRNA1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000138435

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000138435 Gene Symbol
    CHRNA1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: ACHRA

    • Version: chembl_23

    Alternate Names:
    CHNRA GENE_SYMBOL
    CHRNA1 GENE_SYMBOL
    Acetylcholine receptor subunit alpha UNIPROT

    Gene Info:

    Publications:

  • PharmGKB: CHRNA1

    • Version: 18-August-2020

    Alternate Names:
    PA26487 PharmGKB ID

    Gene Info:

    Publications:

  • GO: CHRNA1

    • Version: 01-February-2022

    Alternate Names:
    ACHRA GO Gene Synonym
    CHNRA GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, ION CHANNEL

    Publications:

  • TTD: Neuronal acetylcholine receptor alpha-1

    • Version: 2020.06.01

    Alternate Names:
    CHRNA1 TTD Gene Abbreviation
    T04689 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: CHRNA1

    • Version: 01-February-2022

    Alternate Names:
    Acetylcholine receptor subunit alpha Gene Name
    P02708 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: