-
CHRNA2 1135 Druggable Genome
Alternate Names:
1135 CHOLINERGIC RECEPTOR NICOTINIC ALPHA 2 SUBUNIT CHRNA2 118502 1956 ENSG00000120903 OTTHUMG00000102083 Q15822 ACHA2_HUMAN NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-2 SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15822] Neuronal acetylcholine receptor alpha-2 T55815 Gene Info:
Target Main Class Receptors Target Subclass Ligand_gated_ion_channels Target Subclass cys-loop Transmembrane Helix Count 4 Target Subclass Channels Target Class Receptors Target Subclass TC:1.A.9 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Type Domain Interpro Short Name Neur_channel Interpro Name Neurotransmitter-gated ion-channel Human Readable Name DRUGGABLE GENOME Interpro Acc IPR006202 Interpro Type Family Interpro Short Name Neur_chan_lig-bd Human Readable Name ION CHANNEL Interpro Acc IPR006201 Interpro Name Neurotransmitter-gated ion-channel ligand-binding Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL DRUGGABLE GENOME Publications:
-
Interaction Score: 34.35
-
Interaction Score: 27.48
-
Interaction Score: 24.04
-
Interaction Score: 13.74
-
Interaction Score: 10.3
-
Interaction Score: 10.3
-
Interaction Score: 8.59
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 8.01
-
Interaction Score: 6.87
-
Interaction Score: 5.15
-
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 4.01
Interaction Types & Directionality:
antagonist (inhibitory) blocker (inhibitory) inhibitor (inhibitory) Interaction Info:
Trial Name AGI-004, mecamylamine transdermal patch, CR Novel drug target Established target Trial Name mecamylamine HCl , TC-5231 -
Interaction Score: 3.43
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 3.43
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name gantacurium chloride Novel drug target Established target -
Interaction Score: 1.72
-
Interaction Score: 0.69
-
- Version: 101_38
Alternate Names:
CHRNA2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 26-July-2011
Alternate Names:
NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-2 SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15822] Description CHRNA2 Display Id ENSG00000120903 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: 11-September-2012
Alternate Names:
ACHA2_HUMAN Uniprot Id 1135 Entrez Gene Id CHRNA2 Uniprot Gene Name Gene Info:
Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Type Domain Gene Categories:
ION CHANNEL, DRUGGABLE GENOME Publications:
-
Alternate Names:
CHRNA2 Gene Symbol Q15822 Uniprot Accession ENSG00000120903 Ensembl Gene Id Gene Info:
Target Main Class Receptors Target Subclass Ligand_gated_ion_channels Target Subclass cys-loop Publications:
-
- Version: January-2014
Alternate Names:
CHRNA2 Gene Symbol Gene Info:
Target Class Receptors Target Subclass TC:1.A.9 Publications:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000120903 Gene Symbol CHRNA2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: 2020.06.01
Alternate Names:
CHRNA2 TTD Gene Abbreviation T55815 TTD Target ID Gene Info:
Publications:
-
Alternate Names:
Neuronal acetylcholine receptor subunit alpha-2 Gene Name Q15822 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications: