CHRNB1 Gene Record

  • CHRNB1 1140 Druggable Genome

    Alternate Names:

    1140
    CHOLINERGIC RECEPTOR NICOTINIC BETA 1 SUBUNIT
    CHRNB1
    ACHRB
    CHRNB
    CMS1D
    CMS2A
    CMS2C
    SCCMS
    100710
    1961
    ENSG00000170175
    OTTHUMG00000108139
    Acetylcholine receptor subunit beta
    P11230
    ACHB_HUMAN
    ACETYLCHOLINE RECEPTOR PROTEIN, BETA SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P11230]

    Gene Info:

    Interpro Acc IPR006202
    Interpro Type Domain
    Interpro Acc IPR006201
    Interpro Name Neurotransmitter-gated ion-channel
    Human Readable Name ION CHANNEL
    Interpro Short Name Neur_channel
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Short Name Neur_chan_lig-bd
    Interpro Type Family
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • DECAMETHONIUM BROMIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    partial agonist (activating)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor partial agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • TUBOCURARINE CHLORIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VECURONIUM BROMIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • METOCURINE IODIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PIPECURONIUM BROMIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIVACURIUM CHLORIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DOXACURIUM CHLORIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SUCCINYLCHOLINE CHLORIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • RAPACURONIUM BROMIDE   CHRNB1

    Interaction Score: 0.88

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ROCURONIUM BROMIDE   CHRNB1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ATRACURIUM BESYLATE   CHRNB1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PANCURONIUM BROMIDE   CHRNB1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CISATRACURIUM BESYLATE   CHRNB1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GALLAMINE TRIETHIODIDE   CHRNB1

    Interaction Score: 0.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Muscle-type nicotinic acetylcholine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000170175

    • Version: 101_38

    Alternate Names:
    CHRNB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P11230

    • Version: 11-September-2012

    Alternate Names:
    1140 Entrez Gene Id
    ENSG00000170175 Ensembl Gene Id
    ACHB_HUMAN Uniprot Id

    Gene Info:
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Acc IPR006202
    Interpro Type Domain

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000170175

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000170175 Ensembl Gene Id
    CHRNB1 Display Id
    ACETYLCHOLINE RECEPTOR PROTEIN, BETA SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P11230] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000170175

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000170175 Gene Symbol
    CHRNB1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: ACHRB

    • Version: chembl_23

    Alternate Names:
    CHRNB GENE_SYMBOL
    CHRNB1 GENE_SYMBOL
    Acetylcholine receptor subunit beta UNIPROT

    Gene Info:

    Publications:

  • IDG: CHRNB1

    • Version: 15-July-2019

    Alternate Names:
    CHRNB1 Gene Symbol

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

  • HumanProteinAtlas: CHRNB1

    • Version: 19.3

    Alternate Names:
    ENSG00000170175 Ensembl Gene ID
    CHRNB Human Protein Atlas Gene Synonym
    Cholinergic receptor nicotinic beta 1 subunit Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

  • Pharos: CHRNB1

    • Version: 01-February-2022

    Alternate Names:
    Acetylcholine receptor subunit beta Gene Name
    P11230 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: