-
CYP17A1 1586 Druggable GenomeClinically Actionable
Alternate Names:
1586 CYTOCHROME P450 FAMILY 17 SUBFAMILY A MEMBER 1 CYP17A1 CPT7 CYP17 P450C17 S17AH 609300 2593 ENSG00000148795 OTTHUMG00000018969 P05093 CP17A_HUMAN STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE Cytochrome P450c17 Steroid 17-alpha-monooxygenase Cytochrome P450-C17 Cytochrome P450 17A1 CYPXVII 17-alpha-hydroxyprogesterone aldolase CYTOCHROME P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P05093] PA27090 T89041 Gene Info:
CancerCommons Reported Gene Name CYP17 Interpro Short Name Cyt_P450 Interpro Acc IPR001128 Interpro Name Cytochrome P450 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Type Family Human Readable Name CYTOCHROME P450 Human Readable Name DRUGGABLE GENOME Target Class Enzymes Target Subclass EC:1.14.99.9 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
DRUGGABLE GENOME CYTOCHROME P450 CLINICALLY ACTIONABLE ENZYME
-
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name orteronel, TAK-700 Reported Cancer Type Prostate -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Reported Cancer Type Prostate -
Interaction Score: 8.83
-
Interaction Score: 8.83
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Cytochrome P450 17A1 inhibitor -
Interaction Score: 8.83
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name CB7630 Novel drug target Established target -
Interaction Score: 8.83
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name TOK-001 Mechanism of Interaction Cytochrome P450 17A1 inhibitor
-
- Version: 101_38
Alternate Names:
CYP17A1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 11-September-2012
Alternate Names:
STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE Uniprot Protein Name CYP17A1 Uniprot Gene Name CP17A_HUMAN Uniprot Id Gene Info:
Interpro Name Cytochrome P450 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Gene Categories:
DRUGGABLE GENOME, CYTOCHROME P450 Publications:
-
- Version: January-2014
Alternate Names:
CYP17A1 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:1.14.99.9 Publications:
-
- Version: 25-July-2013
Alternate Names:
1586 Entrez Gene ID Gene Info:
CancerCommons Reported Gene Name CYP17 Publications:
-
- Version: 26-July-2011
Alternate Names:
ENSG00000148795 Ensembl Gene Id CYP17A1 Display Id CYTOCHROME P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P05093] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
PA27090 PharmGKB ID Gene Info:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000148795 Gene Symbol CYP17A1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
Cytochrome P450c17 UNIPROT S17AH GENE_SYMBOL CYP17A1 GENE_SYMBOL Gene Info:
Publications:
-
- Version: 2020.06.01
Alternate Names:
S17AH TTD Gene Abbreviation T89041 TTD Target ID Gene Info:
Publications:
-
Alternate Names:
Steroid 17-alpha-hydroxylase/17,20 lyase Gene Name P05093 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications:
-
- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: