DIO1 Gene Record

  • DIO1 1733 Druggable Genome

    Alternate Names:

    1733
    IODOTHYRONINE DEIODINASE 1
    DIO1
    5DI
    TXDI1
    147892
    2883
    ENSG00000211452
    OTTHUMG00000008435
    ENSG00000181150
    TYPE I IODOTHYRONINE DEIODINASE (EC 1.97.1.10) (TYPE-I 5'DEIODINASE) (DIOI) (TYPE 1 DI) (5DI). [SOURCE:UNIPROT/SWISSPROT;ACC:P49895]
    ITDI1
    Type-I 5'-deiodinase
    Type 1 DI
    DIOI
    Type I iodothyronine deiodinase
    P49895
    IOD1_HUMAN
    Iodothyronine deiodinase type I
    T16792

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Uniprot Status Swiss-Prot
    Interpro Acc IPR000643
    Interpro Name Iodothyronine deiodinase
    Uniprot Evidence 2: Evidence at transcript level
    Interpro Short Name Iodothyronine_deiodinase
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • PROPYLTHIOURACIL   DIO1

    Interaction Score: 7.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Type I iodothyronine deiodinase (Type-I 5'deiodinase) (DIOI) (Type 1 DI) (5DI) inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • Ensembl: ENSG00000211452

    • Version: 101_38

    Alternate Names:
    DIO1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P49895

    • Version: 11-September-2012

    Alternate Names:
    IOD1_HUMAN Uniprot Id
    DIO1 Uniprot Gene Name
    ENSG00000211452 Ensembl Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR000643
    Interpro Name Iodothyronine deiodinase

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000181150

    • Version: 26-July-2011

    Alternate Names:
    TYPE I IODOTHYRONINE DEIODINASE (EC 1.97.1.10) (TYPE-I 5'DEIODINASE) (DIOI) (TYPE 1 DI) (5DI). [SOURCE:UNIPROT/SWISSPROT;ACC:P49895] Description
    ENSG00000181150 Ensembl Gene Id
    DIO1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000211452

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000211452 Gene Symbol
    DIO1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: ITDI1

    • Version: chembl_23

    Alternate Names:
    TXDI1 GENE_SYMBOL
    DIO1 GENE_SYMBOL
    Type I iodothyronine deiodinase UNIPROT

    Gene Info:

    Publications:

  • TTD: Iodothyronine deiodinase type I

    • Version: 2020.06.01

    Alternate Names:
    DIO1 TTD Gene Abbreviation
    T16792 TTD Target ID

    Gene Info:

    Publications: