1803 |
DIPEPTIDYL PEPTIDASE 4 |
DPP4 |
ADABP |
ADCP2 |
CD26 |
DPPIV |
TP103 |
102720 |
3009 |
ENSG00000197635 |
OTTHUMG00000132056 |
Dipeptidyl peptidase IV |
Dipeptidyl peptidase 4 membrane form |
Dipeptidyl peptidase 4 soluble form |
Adenosine deaminase complexing protein 2 |
T-cell activation antigen CD26 |
CD_antigen=CD26 |
Dipeptidyl peptidase IV membrane form |
Dipeptidyl peptidase IV soluble form |
ADCP-2 |
DPP IV |
P27487 |
DPP4_HUMAN |
DIPEPTIDYL PEPTIDASE 4 (EC 3.4.14.5) (DIPEPTIDYL PEPTIDASE IV) (DPP IV) (T-CELL ACTIVATION ANTIGEN CD26) (TP103) (ADENOSINE DEAMINASE COMPLEXING PROTEIN-2) (ADABP) [CONTAINS: DIPEPTIDYL PEPTIDASE 4 MEMBRANE FORM (DIPEPTIDYL PEPTIDASE IV MEMBRANE FORM); DI |
DPP-4 |
T31391 |
Human Readable Name | PROTEASE |
Target Subclass | 3.4.14.5 |
Target Main Class | Enzymes |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:3.4.14.5 |
Interpro Type | Domain |
Interpro Name | Peptidase S9, prolyl oligopeptidase, catalytic domain |
Interpro Acc | IPR001375 |
Interpro Short Name | Peptidase_S9 |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
PROTEASE |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Trial Name | Saxagliptin |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | vildagliptin, LAF 237,Galvus, Equa |
Novel drug target | Established target |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
n/a |
Trial Name | dutogliptin, PHX1149 |
Novel drug target | Established target |
n/a |
Novel drug target | Established target |
Trial Name | KRP-104 |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | alogliptin, SYR-322,Nesina |
antibody (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Dipeptidyl peptidase IV inhibitor |
Direct Interaction | yes |
DPP4 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
DIPEPTIDYL PEPTIDASE 4 (EC 3.4.14.5) (DIPEPTIDYL PEPTIDASE IV) (DPP IV) (T-CELL ACTIVATION ANTIGEN CD26) (TP103) (ADENOSINE DEAMINASE COMPLEXING PROTEIN-2) (ADABP) [CONTAINS: DIPEPTIDYL PEPTIDASE 4 MEMBRANE FORM (DIPEPTIDYL PEPTIDASE IV MEMBRANE FORM); DI | Description |
ENSG00000197635 | Ensembl Gene Id |
DPP4 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
1803 | Entrez Gene Id |
DPP4 | Uniprot Gene Name |
P27487 | Uniprot Accession |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Name | Peptidase S9, prolyl oligopeptidase, catalytic domain |
PROTEASE, DRUGGABLE GENOME |
DPP4 | Gene Symbol |
ENSG00000197635 | Ensembl Gene Id |
1803 | Entrez Gene Id |
Target Subclass | 3.4.14.5 |
Target Main Class | Enzymes |
DPP4 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.4.14.5 |
DPP-4 | TTD Gene Abbreviation |
T31391 | TTD Target ID |
ENSG00000197635 | Gene Symbol |
DPP4 | Ensembl Id |
DRUGGABLE GENOME |
CD26 | GENE_SYMBOL |
DPP4 | GENE_SYMBOL |
Dipeptidyl peptidase 4 | UNIPROT |
ADCP2 | GO Gene Synonym |
CD26 | GO Gene Synonym |
CELL SURFACE |
1803 | Gene ID |
ADABP | dGene Synonym |
ADCP2 | dGene Synonym |
PROTEASE |