1910 |
ENDOTHELIN RECEPTOR TYPE B |
EDNRB |
ABCDS |
ET-B |
ET-BR |
ETB |
ETB1 |
ETBR |
ETRB |
HSCR |
HSCR2 |
WS4A |
131244 |
3180 |
ENSG00000136160 |
OTTHUMG00000017111 |
EDNRB_HUMAN |
P24530 |
Endothelin receptor non-selective type |
Endothelin B receptor |
ENDOTHELIN B RECEPTOR PRECURSOR (ET-B) (ENDOTHELIN RECEPTOR NON- SELECTIVE TYPE). [SOURCE:UNIPROT/SWISSPROT;ACC:P24530] |
T92828 |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Interpro Type | Family |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR000276 |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
Target Main Class | Receptors |
Transmembrane Helix Count | 7 |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Trial Name | macitentan, ACT-064992 |
Novel drug target | Established target |
Direct Interaction | yes |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | Tracleer |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | Letairis |
Novel drug target | Established target |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Endothelin receptor ET-B antagonist |
Direct Interaction | yes |
n/a |
Trial Name | SPI-1620 |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Endothelin receptor ET-B antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Endothelin receptor ET-B antagonist |
Direct Interaction | yes |
EDNRB | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
EDNRB | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
ENSG00000136160 | Ensembl Gene Id |
1910 | Entrez Gene Id |
ENDOTHELIN B RECEPTOR | Uniprot Protein Name |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Interpro Name | GPCR, rhodopsin-like, 7TM |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
P24530 | Uniprot Accession |
1910 | Entrez Gene Id |
EDNRB_HUMAN | Uniprot Id |
Target Main Class | Receptors |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
ENDOTHELIN B RECEPTOR PRECURSOR (ET-B) (ENDOTHELIN RECEPTOR NON- SELECTIVE TYPE). [SOURCE:UNIPROT/SWISSPROT;ACC:P24530] | Description |
EDNRB | Display Id |
ENSG00000136160 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ETRB | GENE_SYMBOL |
EDNRB | GENE_SYMBOL |
Endothelin B receptor | UNIPROT |
ENSG00000136160 | Gene Symbol |
EDNRB | Ensembl Id |
DRUGGABLE GENOME |
1910 | Gene ID |
ABCDS | dGene Synonym |
ET-B | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
EDNRB | TTD Gene Abbreviation |
T92828 | TTD Target ID |