4072 |
EPITHELIAL CELL ADHESION MOLECULE |
EPCAM |
DIAR5 |
EGP-2 |
EGP314 |
EGP40 |
ESA |
HNPCC8 |
KS1/4 |
KSA |
M4S1 |
MIC18 |
MK-1 |
TACSTD1 |
TROP1 |
185535 |
11529 |
ENSG00000119888 |
OTTHUMG00000128853 |
P16422 |
M1S2 |
GA733-2 |
Major gastrointestinal tumor-associated protein GA733-2 |
Tumor-associated calcium signal transducer 1 |
CD_antigen=CD326 |
Ep-CAM |
EGP |
hEGP314 |
KS 1/4 antigen |
Epithelial glycoprotein 314 |
Epithelial glycoprotein |
Epithelial cell surface antigen |
Cell surface glycoprotein Trop-1 |
Adenocarcinoma-associated antigen |
P16642 |
T47863 |
Ber-Ep4 |
BerEp4 |
MOC-31 |
Target Class | Miscellaneous |
Target Subclass | StructuralAndAdhesion |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
n/a |
Mechanism of Interaction | Epithelial cell adhesion molecule other |
Direct Interaction | yes |
Trial Name | ING-1 |
n/a |
Trial Name | VB6-845 |
Novel drug target | Novel Target |
Mechanism of Interaction | Epithelial cell adhesion molecule binding agent |
inhibitor (inhibitory) |
Trial Name | adecatumumab, MT201 |
Novel drug target | Novel Target |
Mechanism of Interaction | Epithelial cell adhesion molecule inhibitor |
n/a |
Trial Name | VB4-845,Proxinium, Vicinium |
Novel drug target | Novel Target |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Epithelial cell adhesion molecule other |
Direct Interaction | yes |
ligand |
antibody (inhibitory) |
Notes | EP-CAM/CD3 Bispecific antibody construct (BITE) |
Trial Name | catumaxomab,Removab |
Novel drug target | Novel Target |
antibody (inhibitory) |
Notes | |
Trial Name | MT110 |
Novel drug target | Novel Target |
EPCAM | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
EPCAM | Gene Symbol |
Target Class | Miscellaneous |
Target Subclass | StructuralAndAdhesion |
EPCAM | Gene Symbol |
Target Class | Miscellaneous |
Target Subclass | StructuralAndAdhesion |
EPCAM | TTD Gene Abbreviation |
T47863 | TTD Target ID |
ENSG00000119888 | Gene Symbol |
EPCAM | Ensembl Id |
DRUGGABLE GENOME |
EP-CAM | Gene Symbol |
M1S2 | GENE_SYMBOL |
M4S1 | GENE_SYMBOL |
MIC18 | GENE_SYMBOL |
GA733-2 | GO Gene Synonym |
M1S2 | GO Gene Synonym |
M4S1 | GO Gene Synonym |
CELL SURFACE |
EPCAM | Gene Symbol |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |