1969 |
EPH RECEPTOR A2 |
EPHA2 |
ARCC2 |
CTPA |
CTPP1 |
CTRCT6 |
ECK |
176946 |
3386 |
ENSG00000142627 |
OTTHUMG00000009527 |
P29317 |
EPHA2_HUMAN |
EPHRIN TYPE-A RECEPTOR 2 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR ECK) (EPITHELIAL CELL KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P29317] |
Tyrosine-protein kinase receptor ECK |
Epithelial cell kinase |
Ephrin type-A receptor 2 |
T57278 |
Target Subclass | Kinase |
Target Subclass | Eph |
Transmembrane Helix Count | 1 |
Target Main Class | Receptors |
Human Readable Name | DRUGGABLE GENOME |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Human Readable Name | KINASE |
Interpro Acc | IPR001245 |
Interpro Type | Domain |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
KINASE |
TYROSINE KINASE |
DRUGGABLE GENOME |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Clinical Status | preclinical |
Pathway | activation |
Variant Effect | gain-of-function |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Ephrin receptor inhibitor |
Direct Interaction | yes |
EPHA2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ENSG00000142627 | Ensembl Gene Id |
1969 | Entrez Gene Id |
P29317 | Uniprot Accession |
Target Subclass | Kinase |
Target Subclass | Eph |
Transmembrane Helix Count | 1 |
EPHA2 | Gene Symbol |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
ENSG00000142627 | Ensembl Gene Id |
EPHA2 | Display Id |
EPHRIN TYPE-A RECEPTOR 2 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR ECK) (EPITHELIAL CELL KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P29317] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
EPHRIN TYPE-A RECEPTOR 2 | Uniprot Protein Name |
EPHA2 | Uniprot Gene Name |
ENSG00000142627 | Ensembl Gene Id |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Human Readable Name | DRUGGABLE GENOME |
Human Readable Name | KINASE |
KINASE, DRUGGABLE GENOME |
ENSG00000142627 | Gene Symbol |
EPHA2 | Ensembl Id |
DRUGGABLE GENOME |
ECK | GENE_SYMBOL |
EPHA2 | GENE_SYMBOL |
Ephrin type-A receptor 2 | UNIPROT |
ECK | GO Gene Synonym |
CELL SURFACE |
EPHA2 | Gene Symbol |
CLINICALLY ACTIONABLE |
1969 | Gene ID |
ARCC2 | dGene Synonym |
CTPA | dGene Synonym |
KINASE, TYROSINE KINASE |
EPHA2 | TTD Gene Abbreviation |
T57278 | TTD Target ID |
Ephrin type-A receptor 2 | Gene Name |
P29317 | UniProt ID |
KINASE |