EPHA8 Gene Record

  • EPHA8 2046 Druggable Genome

    Alternate Names:

    2046
    EPH RECEPTOR A8
    EPHA8
    EEK
    EK3
    HEK3
    176945
    3391
    ENSG00000070886
    OTTHUMG00000002892
    P29322
    EPHA8_HUMAN
    KIAA1459
    EPH-like kinase 3
    Tyrosine-protein kinase receptor EEK
    Ephrin type-A receptor 8
    EPH- and ELK-related kinase
    EPHRIN TYPE-A RECEPTOR 8 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR EEK) (EPH-AND ELK-RELATED KINASE) (HEK3). [SOURCE:UNIPROT/SWISSPROT;ACC:P29322]

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME

    Publications:

  • GENISTEIN   EPHA8

    Interaction Score: 1.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15850105


    Sources:
    NCI

  • VANDETANIB   EPHA8

    Interaction Score: 0.57

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Ephrin receptor inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000070886

    • Version: 101_38

    Alternate Names:
    EPHA8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000070886

    • Version: 26-July-2011

    Alternate Names:
    EPHA8 Display Id
    EPHRIN TYPE-A RECEPTOR 8 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR EEK) (EPH-AND ELK-RELATED KINASE) (HEK3). [SOURCE:UNIPROT/SWISSPROT;ACC:P29322] Description
    ENSG00000070886 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P29322

    • Version: 11-September-2012

    Alternate Names:
    2046 Entrez Gene Id
    ENSG00000070886 Ensembl Gene Id
    EPHA8_HUMAN Uniprot Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • NCI: EPHA8

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Beard et al., 2005, The effects of genistein concentrations on Hep-2 cellular function., Biomed Sci Instrum

  • ChemblInteractions: EEK

    • Version: chembl_23

    Alternate Names:
    HEK3 GENE_SYMBOL
    KIAA1459 GENE_SYMBOL
    EPHA8 GENE_SYMBOL

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000070886

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000070886 Gene Symbol
    EPHA8 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: EPHA8

    • Version: 27-Jun-2013

    Alternate Names:
    2046 Gene ID
    EEK dGene Synonym
    EK3 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • Pharos: EPHA8

    • Version: 01-February-2022

    Alternate Names:
    Ephrin type-A receptor 8 Gene Name
    P29322 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: