ERG Gene Record

  • ERG 2078 Druggable GenomeClinically Actionable

    Alternate Names:

    2078
    ERG, ETS TRANSCRIPTION FACTOR
    ERG
    erg-3
    p55
    165080
    3446
    ENSG00000157554
    OTTHUMG00000090767
    ERG1
    Potassium voltage-gated channel subfamily H member 2
    Eag-related protein 1
    Ether-a-go-go-related gene potassium channel 1
    Eag homolog
    hERG-1
    HERG
    KCNH2
    hERG1
    Ether-a-go-go-related protein 1
    ERG-1
    Voltage-gated potassium channel subunit Kv11.1
    H-ERG
    ETS TRANSCRIPTION FACTOR ERG

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE

    Publications:

  • N-ACETYLASPARTIC ACID   ERG

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZD7009   ERG

    Interaction Score: 0.98

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction HERG blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SOTALOL HYDROCHLORIDE   ERG

    Interaction Score: 0.74

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction HERG blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AMIODARONE HYDROCHLORIDE   ERG

    Interaction Score: 0.59

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction HERG blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AZD1305   ERG

    Interaction Score: 0.49

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction HERG blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PERGOLIDE MESYLATE   ERG

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL146525   ERG

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MITONAFIDE   ERG

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL581225   ERG

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 1,4-DIMETHOXYANTHRAQUINONE   ERG

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOFETILIDE   ERG

    Interaction Score: 0.27

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction HERG blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • IDARUBICIN HYDROCHLORIDE   ERG

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MEDROXYPROGESTERONE ACETATE   ERG

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL585591   ERG

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HOMIDIUM BROMIDE   ERG

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DAUNORUBICIN HYDROCHLORIDE   ERG

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TEDISAMIL   ERG

    Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GUANIDINE HYDROCHLORIDE   ERG

    Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DALFAMPRIDINE   ERG

    Interaction Score: 0.07

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CHEMBL429095   ERG

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NERISPIRDINE   ERG

    Interaction Score: 0.06

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated potassium channel blocker

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000157554

    • Version: 101_38

    Alternate Names:
    ERG Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • ChemblInteractions: ERG

    • Version: chembl_23

    Alternate Names:
    ERG1 GENE_SYMBOL
    HERG GENE_SYMBOL
    KCNH2 GENE_SYMBOL

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000157554

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000157554 Gene Symbol
    ERG Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Tempus: ERG

    • Version: 11-November-2018

    Alternate Names:
    ERG Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • MskImpact: ERG

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • DTC: ERG

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • FoundationOneGenes: ERG

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: ERG

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • Oncomine: ERG

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: