DGIdb - GAPDH Gene Record

GAPDH 2597 Druggable Genome

Alternate Names:

2597
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
GAPDH
G3PD
GAPD
HEL-S-162eP
138400
4141
ENSG00000111640
OTTHUMG00000137379
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, LIVER (EC 1.2.1.12) (GAPDH). [SOURCE:UNIPROT/SWISSPROT;ACC:P04406]
G3P2_HUMAN
P04406
GAPDA
T39321

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Target Class	Enzymes
Target Subclass	EC:1.2.1.12
Target Subclass	2.6.99.-
Gene Biotype	PROTEIN_CODING

(4 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

Graven et al., 1998, Hypoxic regulation of endothelial glyceraldehyde-3-phosphate dehydrogenase., Am. J. Physiol.
Robertson et al., 1998, Tamoxifen up-regulates oestrogen receptor-alpha, c-fos and glyceraldehyde 3-phosphate-dehydrogenase mRNAs in ovine endometrium., J. Steroid Biochem. Mol. Biol.

OMIGAPIL GAPDH

Interaction Score: 4.12

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name omigapil, SNT-317

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial TTD
CHEMBL502775 GAPDH

Interaction Score: 2.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DEFEROXAMINE GAPDH

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9486123

Sources:
NCI
CHEMBL580421 GAPDH

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL139935 GAPDH

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GALLIC ACID GAPDH

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ESTRADIOL GAPDH

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9883985

Sources:
NCI
THIRAM GAPDH

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL601757 GAPDH

Interaction Score: 0.17

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
9,10-PHENANTHRENEQUINONE GAPDH

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TAMOXIFEN GAPDH

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9883985

Sources:
NCI
CHEMBL578512 GAPDH

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL505670 GAPDH

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PURPUROGALLIN GAPDH

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL429095 GAPDH

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000111640
- Version: 101_38
Alternate Names:

GAPDH Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
RussLampel: ENSG00000111640
- Version: 26-July-2011
Alternate Names:

ENSG00000111640 Ensembl Gene Id

G3P2_HUMAN Display Id

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, LIVER (EC 1.2.1.12) (GAPDH). [SOURCE:UNIPROT/SWISSPROT;ACC:P04406] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
TdgClinicalTrial: P04406
- Version: January-2014
Alternate Names:

GAPDA Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:1.2.1.12

Target Subclass 2.6.99.-

Publications:

NCI: GAPDH

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Swearengin et al., 2006, Sevoflurane modulates the activity of glyceraldehyde 3-phosphate dehydrogenase., J Enzyme Inhib Med Chem

Ranganna et al., 1997, Inhibition of platelet-derived growth factor BB-induced expression of glyceraldehyde-3-phosphate dehydrogenase by sodium butyrate in rat vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.

Ogasawara et al., 2005, Characterization of potential selenium-binding proteins in the selenophosphate synthetase system., Proc. Natl. Acad. Sci. U.S.A.

HingoraniCasas: ENSG00000111640
- Version: 31-May-2017
Alternate Names:

ENSG00000111640 Gene Symbol

GAPDH Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TTD: Glyceraldehyde-3-phosphate dehydrogenase
- Version: 2020.06.01
Alternate Names:

GAPDH TTD Gene Abbreviation

T39321 TTD Target ID

Gene Info:

Publications:
Pharos: GAPDH
- Version: 01-February-2022
Alternate Names:

Glyceraldehyde-3-phosphate dehydrogenase Gene Name

P04406 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:
DTC: GAPDH
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

ENSG00000111640	Ensembl Gene Id
G3P2_HUMAN	Display Id
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, LIVER (EC 1.2.1.12) (GAPDH). [SOURCE:UNIPROT/SWISSPROT;ACC:P04406]	Description

Glyceraldehyde-3-phosphate dehydrogenase	Gene Name
P04406	UniProt ID

Trial Name	omigapil, SNT-317
Novel drug target	Novel Target

GAPDH Gene Record

GAPDH 2597 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info: Trial Name omigapil, SNT-317 Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9486123

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9883985

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9883985

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Ensembl: ENSG00000111640

Alternate Names: GAPDH Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000111640

Alternate Names: ENSG00000111640 Ensembl Gene Id G3P2_HUMAN Display Id GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, LIVER (EC 1.2.1.12) (GAPDH). [SOURCE:UNIPROT/SWISSPROT;ACC:P04406] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

TdgClinicalTrial: P04406

Alternate Names: GAPDA Gene Symbol

Gene Info: Target Class Enzymes Target Subclass EC:1.2.1.12 Target Subclass 2.6.99.-

Publications:

NCI: GAPDH

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name omigapil, SNT-317

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9486123

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9883985

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9883985

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

GAPDH Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000111640 Ensembl Gene Id

G3P2_HUMAN Display Id

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, LIVER (EC 1.2.1.12) (GAPDH). [SOURCE:UNIPROT/SWISSPROT;ACC:P04406] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

GAPDA Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:1.2.1.12

Target Subclass 2.6.99.-

Alternate Names:

ENSG00000111640 Gene Symbol

GAPDH Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

GAPDH TTD Gene Abbreviation

T39321 TTD Target ID

Alternate Names:

Glyceraldehyde-3-phosphate dehydrogenase Gene Name

P04406 UniProt ID

Gene Categories:

ENZYME