2741 |
GLYCINE RECEPTOR ALPHA 1 |
GLRA1 |
HKPX1 |
STHE |
138491 |
4326 |
ENSG00000145888 |
OTTHUMG00000130121 |
GLYCINE RECEPTOR ALPHA-1 CHAIN PRECURSOR (GLYCINE RECEPTOR 48 KDA SUBUNIT) (STRYCHNINE BINDING SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P23415] |
P23415 |
GLRA1_HUMAN |
Glycine receptor strychnine-binding subunit |
Glycine receptor 48 kDa subunit |
Glycine receptor subunit alpha-1 |
Strychnine-binding glycine receptor |
T50269 |
Human Readable Name | DRUGGABLE GENOME |
Target Main Class | Receptors |
Transmembrane Helix Count | 3 |
Target Subclass | Channels |
Target Subclass | Ligand_gated_ion_channels |
Target Subclass | cys-loop |
Target Class | Receptors |
Target Subclass | TC:1.A.9.3.1 |
Uniprot Status | Swiss-Prot |
Interpro Type | Family |
Human Readable Name | ION CHANNEL |
Interpro Short Name | Neur_channel |
Interpro Acc | IPR006202 |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR006201 |
Interpro Type | Domain |
Interpro Short Name | Neur_chan_lig-bd |
Interpro Name | Neurotransmitter-gated ion-channel ligand-binding |
Interpro Name | Neurotransmitter-gated ion-channel |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
agonist (activating) |
Novel drug target | Established target |
Trial Name | - |
Direct Interaction | yes |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
agonist (activating) |
potentiator |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
Direct Interaction | yes |
Trial Name | - |
agonist (activating) |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) agonist |
Direct Interaction | yes |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
allosteric modulator |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
Direct Interaction | yes |
GLRA1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
GLRA1 | Display Id |
GLYCINE RECEPTOR ALPHA-1 CHAIN PRECURSOR (GLYCINE RECEPTOR 48 KDA SUBUNIT) (STRYCHNINE BINDING SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P23415] | Description |
ENSG00000145888 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
GLRA1 | Gene Symbol |
P23415 | Uniprot Accession |
2741 | Entrez Gene Id |
Transmembrane Helix Count | 3 |
Target Subclass | Channels |
Target Subclass | Ligand_gated_ion_channels |
GLRA1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | TC:1.A.9.3.1 |
GLRA1_HUMAN | Uniprot Id |
ENSG00000145888 | Ensembl Gene Id |
P23415 | Uniprot Accession |
Uniprot Status | Swiss-Prot |
Interpro Type | Family |
Human Readable Name | ION CHANNEL |
ION CHANNEL, DRUGGABLE GENOME |
GLRA1 | GENE_SYMBOL |
Glycine receptor subunit alpha-1 | UNIPROT |
Glycine receptor 48 kDa subunit | UNIPROT |
ENSG00000145888 | Gene Symbol |
GLRA1 | Ensembl Id |
DRUGGABLE GENOME |
GLRA1 | TTD Gene Abbreviation |
T50269 | TTD Target ID |
Glycine receptor subunit alpha-1 | Gene Name |
P23415 | UniProt ID |
ION CHANNEL |
EXTERNAL SIDE OF PLASMA MEMBRANE |