-
GRIK1 2897 Druggable Genome
Alternate Names:
2897 GLUTAMATE IONOTROPIC RECEPTOR KAINATE TYPE SUBUNIT 1 GRIK1 EAA3 EEA3 GLR5 GLUR5 GluK1 gluR-5 138245 4579 ENSG00000171189 OTTHUMG00000078879 GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 PRECURSOR (GLUTAMATE RECEPTOR 5) (GLUR-5) (GLUR5) (EXCITATORY AMINO ACID RECEPTOR 3) (EAA3). [SOURCE:UNIPROT/SWISSPROT;ACC:P39086] Excitatory amino acid receptor 3 Glutamate receptor 5 Glutamate receptor ionotropic, kainate 1 P39086 GRIK1_HUMAN GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 PA28973 Glutamate receptor ionotropic kainate 1 T73495 Gene Info:
Human Readable Name DRUGGABLE GENOME Target Class Receptors Target Subclass TC:1.A.10.1 Target Subclass Channels Target Subclass Ligand_gated_ion_channels Target Main Class Receptors Transmembrane Helix Count 3 Target Subclass Glutamate Interpro Short Name Iontro_glu_rcpt Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Name Ionotropic glutamate receptor Interpro Type Domain Interpro Acc IPR001320 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL DRUGGABLE GENOME Publications:
-
Interaction Score: 4.12
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist Trial Name tezampanel, NGX424,NGX426 -
Interaction Score: 3.32
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name topiramate controlled release,Trokesa Novel drug target Established target Trial Name topiramate tablet,Topamax -
Interaction Score: 2.47
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Glutamate receptor ionotropic kainate 1 antagonist Direct Interaction yes -
Interaction Score: 1.55
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist Direct Interaction yes
-
- Version: 101_38
Alternate Names:
GRIK1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 26-July-2011
Alternate Names:
GRIK1 Display Id GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 PRECURSOR (GLUTAMATE RECEPTOR 5) (GLUR-5) (GLUR5) (EXCITATORY AMINO ACID RECEPTOR 3) (EAA3). [SOURCE:UNIPROT/SWISSPROT;ACC:P39086] Description ENSG00000171189 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: January-2014
Alternate Names:
GRIK1 Gene Symbol Gene Info:
Target Class Receptors Target Subclass TC:1.A.10.1 Publications:
-
Alternate Names:
GRIK1 Gene Symbol P39086 Uniprot Accession ENSG00000171189 Ensembl Gene Id Gene Info:
Target Subclass Channels Target Subclass Ligand_gated_ion_channels Target Main Class Receptors Publications:
-
- Version: 11-September-2012
Alternate Names:
P39086 Uniprot Accession GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 Uniprot Protein Name GRIK1 Uniprot Gene Name Gene Info:
Interpro Short Name Iontro_glu_rcpt Human Readable Name DRUGGABLE GENOME Uniprot Evidence 1: Evidence at protein level Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
PA28973 PharmGKB ID Gene Info:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000171189 Gene Symbol GRIK1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
GLUR5 GENE_SYMBOL GRIK1 GENE_SYMBOL Glutamate receptor ionotropic, kainate 1 UNIPROT Gene Info:
Publications:
-
- Version: 2020.06.01
Alternate Names:
GRIK1 TTD Gene Abbreviation T73495 TTD Target ID Gene Info:
Publications:
-
Alternate Names:
Glutamate receptor ionotropic, kainate 1 Gene Name P39086 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications: