• GRIK3 2899 Druggable Genome

    Alternate Names:

    2899
    GLUTAMATE IONOTROPIC RECEPTOR KAINATE TYPE SUBUNIT 3
    GRIK3
    EAA5
    GLR7
    GLUR7
    GluK3
    GluR7a
    138243
    4581
    ENSG00000163873
    OTTHUMG00000004189
    GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 3 PRECURSOR (GLUTAMATE RECEPTOR 7) (GLUR-7) (GLUR7) (EXCITATORY AMINO ACID RECEPTOR 5) (EAA5). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13003]
    Q13003
    Excitatory amino acid receptor 5
    Glutamate receptor ionotropic, kainate 3
    Glutamate receptor 7
    GluR-7
    GRIK3_HUMAN
    GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 3
    PA28975

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR001320
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Short Name Iontro_glu_rcpt
    Interpro Name Ionotropic glutamate receptor
    Target Class Receptors
    Target Subclass TC:1.A.10.1
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 4.58

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name tezampanel, NGX424,NGX426
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist

    PMIDs:
    None found


  • Interaction Score: 2.58

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist

    PMIDs:
    None found


  • Interaction Score: 0.5

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Direct Interaction yes

    PMIDs:
    None found