116443 |
GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 3A |
GRIN3A |
GluN3A |
NMDAR-L |
NR3A |
606650 |
16767 |
ENSG00000198785 |
OTTHUMG00000020387 |
Q8TCU5 |
KIAA1973 |
N-methyl-D-aspartate receptor subtype 3A |
NMDAR3A |
Glutamate receptor ionotropic, NMDA 3A |
NMD3A_HUMAN |
GLUTAMATE [NMDA] RECEPTOR SUBUNIT 3A PRECURSOR (N-METHYL-D-ASPARTATE RECEPTOR SUBTYPE NR3A) (NMDAR-L). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8TCU5] |
GLUTAMATE [NMDA] RECEPTOR SUBUNIT 3A |
PA28983 |
Transmembrane Helix Count | 4 |
Target Subclass | Channels |
Target Main Class | Receptors |
Target Subclass | Glutamate |
Target Subclass | Ligand_gated_ion_channels |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR001320 |
Interpro Short Name | Iontro_glu_rcpt |
Interpro Name | Ionotropic glutamate receptor |
Interpro Type | Domain |
Target Class | Receptors |
Target Subclass | TC:1.A.10.1 |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
n/a |
Trial Name | acamprosate,Campral |
Novel drug target | Established target |
n/a |
Trial Name | neramexane mesylate |
Novel drug target | Established target |
n/a |
Mechanism of Interaction | Glutamate [NMDA] receptor negative allosteric modulator |
Direct Interaction | yes |
Trial Name | AM-101 |
blocker (inhibitory) |
Novel drug target | Established target |
Trial Name | AZD-6765 |
Mechanism of Interaction | Glutamate [NMDA] receptor blocker |
blocker (inhibitory) |
Novel drug target | Established target |
Trial Name | CNS-5161 |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | V3381 |
Novel drug target | Established target |
Direct Interaction | yes |
partial agonist (activating) |
Mechanism of Interaction | Glutamate [NMDA] receptor partial agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | Glutamate [NMDA] receptor positive allosteric modulator |
Direct Interaction | yes |
partial agonist (activating) |
Mechanism of Interaction | Glutamate [NMDA] receptor partial agonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Glutamate [NMDA] receptor negative allosteric modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Glutamate [NMDA] receptor negative allosteric modulator |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
n/a |
Trial Name | dexanabinol, HU-211 |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Glutamate [NMDA] receptor negative allosteric modulator |
Direct Interaction | yes |
n/a |
Trial Name | Dimebon |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate [NMDA] receptor antagonist |
GRIN3A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
GRIN3A | Gene Symbol |
Q8TCU5 | Uniprot Accession |
116443 | Entrez Gene Id |
Transmembrane Helix Count | 4 |
Target Subclass | Channels |
Target Main Class | Receptors |
GRIN3A | Display Id |
GLUTAMATE [NMDA] RECEPTOR SUBUNIT 3A PRECURSOR (N-METHYL-D-ASPARTATE RECEPTOR SUBTYPE NR3A) (NMDAR-L). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8TCU5] | Description |
ENSG00000198785 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
GRIN3A | Gene Symbol |
Target Class | Receptors |
Target Subclass | TC:1.A.10.1 |
GLUTAMATE [NMDA] RECEPTOR SUBUNIT 3A | Uniprot Protein Name |
NMD3A_HUMAN | Uniprot Id |
ENSG00000198785 | Ensembl Gene Id |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR001320 |
DRUGGABLE GENOME |
PA28983 | PharmGKB ID |
ENSG00000198785 | Gene Symbol |
GRIN3A | Ensembl Id |
DRUGGABLE GENOME |
KIAA1973 | GENE_SYMBOL |
GRIN3A | GENE_SYMBOL |
Glutamate receptor ionotropic, NMDA 3A | UNIPROT |
Glutamate receptor ionotropic, NMDA 3A | Gene Name |
Q8TCU5 | UniProt ID |
ION CHANNEL |