GSK3A Gene Record

  • GSK3A 2931 Druggable Genome

    Alternate Names:

    2931
    GLYCOGEN SYNTHASE KINASE 3 ALPHA
    GSK3A
    606784
    4616
    ENSG00000105723
    OTTHUMG00000150722
    P49840
    GSK3A_HUMAN
    GLYCOGEN SYNTHASE KINASE-3 ALPHA (EC 2.7.1.37) (GSK-3 ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49840]
    GLYCOGEN SYNTHASE KINASE-3 ALPHA
    GSK-3 alpha
    Serine/threonine-protein kinase GSK3A
    T76910
    GSK-3A
    -

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Acc IPR002290
    Uniprot Status Swiss-Prot
    Target Class Enzymes
    Target Subclass EC:2.7.11.26
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    TRANSCRIPTION FACTOR

    Publications:

  • TIDEGLUSIB   GSK3A

    Interaction Score: 1.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name tideglusib, NP-12,Nypta
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • CHEMBL259850   GSK3A

    Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC TTD

  • LITHIUM CITRATE   GSK3A

    Interaction Score: 0.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • LITHIUM CARBONATE   GSK3A

    Interaction Score: 0.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glycogen synthase kinase-3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CHEMBL1276446   GSK3A

    Interaction Score: 0.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL588859   GSK3A

    Interaction Score: 0.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHIR-99021   GSK3A

    Interaction Score: 0.43

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC TTD

  • AZAKENPAULLONE   GSK3A

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LY-2090314   GSK3A

    Interaction Score: 0.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glycogen synthase kinase-3 alpha inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • BMS-387032   GSK3A

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZD-1080   GSK3A

    Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glycogen synthase kinase-3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • KENPAULLONE   GSK3A

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC TTD

  • SB-220025   GSK3A

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL546797   GSK3A

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL541400   GSK3A

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GO-6976   GSK3A

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   GSK3A

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   GSK3A

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • JNJ-7706621   GSK3A

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SOTRASTAURIN   GSK3A

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   GSK3A

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   GSK3A

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   GSK3A

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   GSK3A

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   GSK3A

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   GSK3A

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000105723

    • Version: 101_38

    Alternate Names:
    GSK3A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P49840

    • Version: January-2014

    Alternate Names:
    GSK3A Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.26

    Publications:

  • RussLampel: ENSG00000105723

    • Version: 26-July-2011

    Alternate Names:
    GSK3A Display Id
    ENSG00000105723 Ensembl Gene Id
    GLYCOGEN SYNTHASE KINASE-3 ALPHA (EC 2.7.1.37) (GSK-3 ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49840] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P49840

    • Version: 11-September-2012

    Alternate Names:
    GSK3A_HUMAN Uniprot Id
    ENSG00000105723 Ensembl Gene Id
    P49840 Uniprot Accession

    Gene Info:
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: GSK3A

    • Version: chembl_23

    Alternate Names:
    GSK3A GENE_SYMBOL
    Glycogen synthase kinase-3 alpha UNIPROT
    Serine/threonine-protein kinase GSK3A UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000105723

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000105723 Gene Symbol
    GSK3A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: GSK3A

    • Version: 27-Jun-2013

    Alternate Names:
    2931 Gene ID
    - dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Glycogen synthase kinase-3 alpha

    • Version: 2020.06.01

    Alternate Names:
    GSK-3A TTD Gene Abbreviation
    T76910 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: GSK3A

    • Version: 01-February-2022

    Alternate Names:
    Glycogen synthase kinase-3 alpha Gene Name
    P49840 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

  • DTC: GSK3A

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • GO: GSK3A

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications: