HBB Gene Record

  • HBB 3043 Druggable Genome

    Alternate Names:

    3043
    HEMOGLOBIN SUBUNIT BETA
    HBB
    CD113t-C
    beta-globin
    141900
    4827
    ENSG00000244734
    OTTHUMG00000066678
    Spinorphin
    LVV-hemorphin-7
    Hemoglobin beta chain
    P68871
    HEMOGLOBIN
    PA29202
    T31825
    HB
    T49493
    ECYT6

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass hemoglobin
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

  • VOXELOTOR   HBB

    Interaction Score: 6.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB TTD FDA

  • AES-103   HBB

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name AES-103
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • DEFERITAZOLE   HBB

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SODIUM 2,2-DIMETHYLBUTYRATE   HBB

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • EFAPROXIRAL   HBB

    Interaction Score: 2.21

    Interaction Types & Directionality:
    negative modulator (inhibitory)

    Interaction Info:
    Mechanism of Interaction Hemoglobin HbA negative modulator
    Direct Interaction yes

    PMIDs:
    10592235


    Sources:
    ChemblInteractions

  • NEBULARINE   HBB

    Interaction Score: 1.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HYDROXYCAMPTOTHECIN   HBB

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL458765   HBB

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL54918   HBB

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 8-AZAGUANINE   HBB

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIOINOSINE   HBB

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL374632   HBB

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOPOTECAN HYDROCHLORIDE   HBB

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUINACRINE DIHYDROCHLORIDE   HBB

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENAZOPYRIDINE HYDROCHLORIDE   HBB

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL605003   HBB

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENYLMERCURIC ACETATE   HBB

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MERCURIC CHLORIDE   HBB

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL515505   HBB

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZATHIOPRINE   HBB

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIOGUANINE   HBB

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MENADIONE   HBB

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ELLAGIC ACID   HBB

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ELLIPTECINE   HBB

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZACITIDINE   HBB

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CAMPTOTHECIN   HBB

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MERCAPTOPURINE   HBB

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FLUOROURACIL   HBB

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000244734

    • Version: 101_38

    Alternate Names:
    HBB Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P68871

    • Version: January-2014

    Alternate Names:
    HBB Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Miscellaneous
    Target Subclass hemoglobin

    Publications:

  • TTD: Hemoglobin

    • Version: 2020.06.01

    Alternate Names:
    HB TTD Gene Abbreviation
    T49493 TTD Target ID

    Gene Info:

    Publications:
    Apte SS, 2008, Blood substitutes--the polyheme trials., Mcgill J Med

  • ChemblInteractions: HBB

    • Version: chembl_23

    Alternate Names:
    HBB GENE_SYMBOL
    Hemoglobin subunit beta UNIPROT
    LVV-hemorphin-7 UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000244734

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000244734 Gene Symbol
    HBB Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: HBB

    • Version: 18-August-2020

    Alternate Names:
    PA29202 PharmGKB ID

    Gene Info:

    Publications:

  • TTD: Hemoglobin subunit beta

    • Version: 2020.06.01

    Alternate Names:
    HBB TTD Gene Abbreviation
    T31825 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: HBB

    • Version: 01-February-2022

    Alternate Names:
    Hemoglobin subunit beta Gene Name
    P68871 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • DTC: HBB

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • FDA: HBB

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Publications: