3066 |
HISTONE DEACETYLASE 2 |
HDAC2 |
HD2 |
RPD3 |
YAF1 |
605164 |
4853 |
ENSG00000196591 |
OTTHUMG00000015411 |
Q92769 |
HDAC2_HUMAN |
T51191 |
2578 |
KDAC2 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase 2 inhibitor |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase 2 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Trial Name | PCI-27483, CRA-024781 |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Chidamide, HBI-8000 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Panobinostat |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Trial Name | CUDC-101 |
n/a |
Trial Name | 4SC-202 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | ITF2357,Givinostat |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Resminostat |
Novel drug target | Established target |
n/a |
Novel drug target | Established target |
Trial Name | AR-42 |
n/a |
Trial Name | SB939 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
HDAC2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC2 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
HDAC2 | Gene Symbol |
HDAC2_HUMAN | Uniprot Id |
ENSG00000196591 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
3066 | Entrez Gene ID |
2578 | CIViC Gene ID |
ENSG00000196591 | Gene Symbol |
HDAC2 | Ensembl Id |
DRUGGABLE GENOME |
HDAC2 | GENE_SYMBOL |
Histone deacetylase 2 | UNIPROT |
HD2 | UNIPROT |
HDAC2 | Gene Symbol |
HDAC2 | Gene Symbol |
CLINICALLY ACTIONABLE |
HDAC2 | TTD Gene Abbreviation |
T51191 | TTD Target ID |
Histone deacetylase 2 | Gene Name |
Q92769 | UniProt ID |
TRANSCRIPTION FACTOR |