8841 |
HISTONE DEACETYLASE 3 |
HDAC3 |
HD3 |
RPD3 |
RPD3-2 |
605166 |
4854 |
ENSG00000171720 |
OTTHUMG00000129629 |
SMAP45 |
O15379 |
HDAC3_HUMAN |
T05090 |
KDAC3 |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase 3 |
Trial Name | MGCD-0103 |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Trial Name | PXD101 |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase 3 inhibitor |
Notes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
Trial Name | entinostat, SNDX-275, MS-275 |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Chidamide, HBI-8000 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | Panobinostat |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Notes | |
Novel drug target | Established target |
Trial Name | CUDC-101 |
inhibitor (inhibitory) |
Trial Name | Depsipeptide |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Trial Name | PCI-27483, CRA-024781 |
Novel drug target | Established target |
Notes |
n/a |
Trial Name | 4SC-202 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | ITF2357,Givinostat |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Trial Name | Resminostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | SB939 |
Novel drug target | Established target |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
HDAC3 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
8841 | Entrez Gene Id |
O15379 | Uniprot Accession |
ENSG00000171720 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
HDAC3 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
ENSG00000171720 | Gene Symbol |
HDAC3 | Ensembl Id |
DRUGGABLE GENOME |
HDAC3 | Gene Symbol |
HDAC3 | GENE_SYMBOL |
Histone deacetylase 3 | UNIPROT |
RPD3-2 | UNIPROT |
HDAC3 | TTD Gene Abbreviation |
T05090 | TTD Target ID |
Histone deacetylase 3 | Gene Name |
O15379 | UniProt ID |
TRANSCRIPTION FACTOR |