9759 |
HISTONE DEACETYLASE 4 |
HDAC4 |
AHO3 |
BDMR |
HA6116 |
HD4 |
HDAC-4 |
HDAC-A |
HDACA |
605314 |
14063 |
ENSG00000068024 |
OTTHUMG00000133344 |
P56524 |
HDAC |
KIAA0288 |
PA29229 |
T63816 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
TRANSCRIPTION FACTOR BINDING |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | PXD101 |
Notes |
n/a |
Novel drug target | Established target |
Trial Name | MGCD-0103 |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Trial Name | CUDC-101 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
Trial Name | Depsipeptide |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Panobinostat |
Notes |
inhibitor (inhibitory) |
Trial Name | ITF2357,Givinostat |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Resminostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Notes |
n/a |
Trial Name | SB939 |
Novel drug target | Established target |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
HDAC4 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC4 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
PA29229 | PharmGKB ID |
HDAC4 | Gene Symbol |
9759 | Entrez Gene Id |
HDAC4 | MyCancerGenome Gene Symbol |
HDAC | MyCancerGenome Reported Gene Name |
ENSG00000068024 | Gene Symbol |
HDAC4 | Ensembl Id |
DRUGGABLE GENOME |
KIAA0288 | GENE_SYMBOL |
HDAC4 | GENE_SYMBOL |
Histone deacetylase 4 | UNIPROT |
KIAA0288 | GO Gene Synonym |
TRANSCRIPTION FACTOR BINDING |
HDAC4 | Gene Symbol |
CLINICALLY ACTIONABLE |
HDAC4 | TTD Gene Abbreviation |
T63816 | TTD Target ID |
Histone deacetylase 4 | Gene Name |
P56524 | UniProt ID |
TRANSCRIPTION FACTOR |
CLINICALLY ACTIONABLE |