55869 |
HISTONE DEACETYLASE 8 |
HDAC8 |
CDA07 |
CDLS5 |
HD8 |
HDACL1 |
MRXS6 |
RPD3 |
WTS |
300269 |
13315 |
ENSG00000147099 |
OTTHUMG00000021814 |
Q9BY41 |
HDAC8_HUMAN |
T28887 |
KDAC8 |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Notes | |
Trial Name | PXD101 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase 8 inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Trial Name | CUDC-101 |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | 4SC-202 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | ITF2357,Givinostat |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes | |
Trial Name | Panobinostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Resminostat |
n/a |
Trial Name | SB939 |
Novel drug target | Established target |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
HDAC8 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
Q9BY41 | Uniprot Accession |
HDAC8 | Gene Symbol |
ENSG00000147099 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
HDAC8 | Gene Symbol |
Target Subclass | EC:3.5.1.98 |
Target Class | Enzymes |
ENSG00000147099 | Gene Symbol |
HDAC8 | Ensembl Id |
DRUGGABLE GENOME |
HDACL1 | GENE_SYMBOL |
HDAC8 | GENE_SYMBOL |
Histone deacetylase 8 | UNIPROT |
HDAC8 | Gene Symbol |
HDAC8 | TTD Gene Abbreviation |
T28887 | TTD Target ID |
Histone deacetylase 8 | Gene Name |
Q9BY41 | UniProt ID |
TRANSCRIPTION FACTOR |