3274 |
HISTAMINE RECEPTOR H2 |
HRH2 |
H2R |
142703 |
5183 |
ENSG00000113749 |
OTTHUMG00000130660 |
Histamine H2 receptor |
Gastric receptor I |
HH2R |
HRH2_HUMAN |
P25021 |
HISTAMINE H2 RECEPTOR (H2R) (GASTRIC RECEPTOR I). [SOURCE:UNIPROT/SWISSPROT;ACC:P25021] |
T30985 |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
Human Readable Name | DRUGGABLE GENOME |
Transmembrane Helix Count | 7 |
Target Main Class | Receptors |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Interpro Acc | IPR000276 |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 2: Evidence at transcript level |
Interpro Type | Family |
Gene Biotype | PROTEIN_CODING |
KINASE |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
Trial Name | - |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Trial Name | HZT-501, ibuprofen + famotidine,Duexa |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | epinastine |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Histamine H2 receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H2 receptor antagonist |
Direct Interaction | yes |
Trial Name | - |
agonist (activating) |
Trial Name | Ceplene |
Novel drug target | Established target |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | Silenor (SO-101) |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | Asenapine |
agonist (activating) |
Mechanism of Interaction | Histamine H2 receptor agonist |
Direct Interaction | yes |
HRH2 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HRH2 | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
HISTAMINE H2 RECEPTOR (H2R) (GASTRIC RECEPTOR I). [SOURCE:UNIPROT/SWISSPROT;ACC:P25021] | Description |
ENSG00000113749 | Ensembl Gene Id |
HRH2 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
HRH2_HUMAN | Uniprot Id |
P25021 | Uniprot Accession |
3274 | Entrez Gene Id |
Target Subclass | Rhodopsin |
Transmembrane Helix Count | 7 |
Target Subclass | GPCR |
ENSG00000113749 | Ensembl Gene Id |
HISTAMINE H2 RECEPTOR | Uniprot Protein Name |
P25021 | Uniprot Accession |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Human Readable Name | DRUGGABLE GENOME |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
ENSG00000113749 | Gene Symbol |
HRH2 | Ensembl Id |
DRUGGABLE GENOME |
HRH2 | GENE_SYMBOL |
Histamine H2 receptor | UNIPROT |
Gastric receptor I | UNIPROT |
3274 | Gene ID |
H2R | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
H2R | TTD Gene Abbreviation |
T30985 | TTD Target ID |
Histamine H2 receptor | Gene Name |
P25021 | UniProt ID |
KINASE |