DGIdb - HSD11B2 Gene Record

HSD11B2 3291 Druggable Genome

Alternate Names:

3291
HYDROXYSTEROID 11-BETA DEHYDROGENASE 2
HSD11B2
AME
AME1
HSD11K
HSD2
SDR9C3
614232
5209
ENSG00000176387
OTTHUMG00000137507
CORTICOSTEROID 11-BETA-DEHYDROGENASE, ISOZYME 2 (EC 1.1.1.-) (11-DH2) (11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2) (11-BETA-HSD2) (NAD- DEPENDENT 11-BETA-HYDROXYSTEROID DEHYDROGENASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P80365]
P80365
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2
DHI2_HUMAN
Corticosteroid 11-beta-dehydrogenase 2
T43721

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Acc	IPR002198
Interpro Type	Family
Interpro Name	Short-chain dehydrogenase/reductase SDR
Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Interpro Short Name	DH_sc/Rdtase_SDR
Human Readable Name	SHORT CHAIN DEHYDROGENASE REDUCTASE
Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
SHORT CHAIN DEHYDROGENASE REDUCTASE
ENZYME

Publications:

Quinkler et al., 2004, Molecular basis for the apparent mineralocorticoid excess syndrome in the Oman population., Mol. Cell. Endocrinol.
Quinkler et al., 2003, Hypertension and the cortisol-cortisone shuttle., J. Clin. Endocrinol. Metab.

HYDROCORTISONE HSD11B2

Interaction Score: 5.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15134813 12788832

Sources:
NCI

Ensembl: ENSG00000176387
- Version: 101_38
Alternate Names:

HSD11B2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P80365
- Version: 11-September-2012
Alternate Names:

ENSG00000176387 Ensembl Gene Id

P80365 Uniprot Accession

CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2 Uniprot Protein Name

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Acc IPR002198

Interpro Type Family

Gene Categories:

DRUGGABLE GENOME, SHORT CHAIN DEHYDROGENASE REDUCTASE

Publications:

RussLampel: ENSG00000176387

Version: 26-July-2011

Alternate Names:

ENSG00000176387 Ensembl Gene Id

CORTICOSTEROID 11-BETA-DEHYDROGENASE, ISOZYME 2 (EC 1.1.1.-) (11-DH2) (11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2) (11-BETA-HSD2) (NAD- DEPENDENT 11-BETA-HYDROXYSTEROID DEHYDROGENASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P80365] Description

HSD11B2 Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

NCI: HSD11B2

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Quinkler et al., 2003, Hypertension and the cortisol-cortisone shuttle., J. Clin. Endocrinol. Metab.

Quinkler et al., 2004, Molecular basis for the apparent mineralocorticoid excess syndrome in the Oman population., Mol. Cell. Endocrinol.

HingoraniCasas: ENSG00000176387
- Version: 31-May-2017
Alternate Names:

ENSG00000176387 Gene Symbol

HSD11B2 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TTD: Corticosteroid 11-beta-dehydrogenase 2
- Version: 2020.06.01
Alternate Names:

HSD11B2 TTD Gene Abbreviation

T43721 TTD Target ID

Gene Info:

Publications:
Pharos: HSD11B2
- Version: 01-February-2022
Alternate Names:

Corticosteroid 11-beta-dehydrogenase isozyme 2 Gene Name

P80365 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

ENSG00000176387	Ensembl Gene Id
P80365	Uniprot Accession
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2	Uniprot Protein Name

Corticosteroid 11-beta-dehydrogenase isozyme 2	Gene Name
P80365	UniProt ID

HSD11B2	TTD Gene Abbreviation
T43721	TTD Target ID

HSD11B2 Gene Record

HSD11B2 3291 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

HYDROCORTISONE HSD11B2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15134813 12788832

Sources: NCI

Ensembl: ENSG00000176387

Alternate Names: HSD11B2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P80365

Alternate Names: ENSG00000176387 Ensembl Gene Id P80365 Uniprot Accession CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2 Uniprot Protein Name

Gene Info: Human Readable Name DRUGGABLE GENOME Interpro Acc IPR002198 Interpro Type Family

Gene Categories: DRUGGABLE GENOME, SHORT CHAIN DEHYDROGENASE REDUCTASE

Publications:

RussLampel: ENSG00000176387

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

NCI: HSD11B2

Alternate Names:

Gene Info:

Publications: Quinkler et al., 2003, Hypertension and the cortisol-cortisone shuttle., J. Clin. Endocrinol. Metab. Quinkler et al., 2004, Molecular basis for the apparent mineralocorticoid excess syndrome in the Oman population., Mol. Cell. Endocrinol.

HingoraniCasas: ENSG00000176387

Alternate Names: ENSG00000176387 Gene Symbol HSD11B2 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

TTD: Corticosteroid 11-beta-dehydrogenase 2

Alternate Names: HSD11B2 TTD Gene Abbreviation T43721 TTD Target ID

Gene Info:

Publications:

Pharos: HSD11B2

Alternate Names: Corticosteroid 11-beta-dehydrogenase isozyme 2 Gene Name P80365 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
15134813 12788832

Sources:
NCI

Alternate Names:

HSD11B2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000176387 Ensembl Gene Id

P80365 Uniprot Accession

CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2 Uniprot Protein Name

Gene Info:

Human Readable Name DRUGGABLE GENOME

Interpro Acc IPR002198

Interpro Type Family

Gene Categories:

DRUGGABLE GENOME, SHORT CHAIN DEHYDROGENASE REDUCTASE

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

Quinkler et al., 2003, Hypertension and the cortisol-cortisone shuttle., J. Clin. Endocrinol. Metab.

Quinkler et al., 2004, Molecular basis for the apparent mineralocorticoid excess syndrome in the Oman population., Mol. Cell. Endocrinol.

Alternate Names:

ENSG00000176387 Gene Symbol

HSD11B2 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

HSD11B2 TTD Gene Abbreviation

T43721 TTD Target ID

Alternate Names:

Corticosteroid 11-beta-dehydrogenase isozyme 2 Gene Name

P80365 UniProt ID

Gene Categories:

ENZYME