3351 |
5-HYDROXYTRYPTAMINE RECEPTOR 1B |
HTR1B |
5-HT-1B |
5-HT-1D-beta |
5-HT1B |
5-HT1DB |
HTR1D2 |
HTR1DB |
S12 |
182131 |
5287 |
ENSG00000135312 |
OTTHUMG00000015066 |
Serotonin 1D beta receptor |
Serotonin receptor 1B |
5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR 1B) (5- HT1B) (5-HT-1D-BETA) (SEROTONIN 1D BETA RECEPTOR) (S12). [SOURCE:UNIPROT/SWISSPROT;ACC:P28222] |
P28222 |
5HT1B_HUMAN |
PA29549 |
5-HT 1B receptor |
T07806 |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Family |
Interpro Acc | IPR000276 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Uniprot Status | Swiss-Prot |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Uniprot Evidence | 1: Evidence at protein level |
Target Main Class | Receptors |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
Transmembrane Helix Count | 7 |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
agonist (activating) |
Trial Name | frovatriptan,Frovelan, Frova |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
Trial Name | zolmitriptan,Zomig |
agonist (activating) |
Trial Name | MT 400,Treximet |
Novel drug target | Established target |
Trial Name | NP101,Zelrix |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | trelanserin, SL 65.0472 |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor antagonist |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
partial agonist (activating) |
agonist (activating) |
Trial Name | Lu AA21004 |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor antagonist |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | Asenapine |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Serotonin 1b (5-HT1b) receptor agonist |
Direct Interaction | yes |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | olanzapine,Zyprexa, Zypadhera, Zyprexa Relprevv |
Novel drug target | Established target |
Trial Name | Olanzapine/fluoxetine combination,Symbyax (Zyprexa/Prozac) |
HTR1B | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR 1B) (5- HT1B) (5-HT-1D-BETA) (SEROTONIN 1D BETA RECEPTOR) (S12). [SOURCE:UNIPROT/SWISSPROT;ACC:P28222] | Description |
ENSG00000135312 | Ensembl Gene Id |
HTR1B | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
HTR1B | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
P28222 | Uniprot Accession |
HTR1B | Gene Symbol |
ENSG00000135312 | Ensembl Gene Id |
Target Main Class | Receptors |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
ENSG00000135312 | Ensembl Gene Id |
5-HYDROXYTRYPTAMINE RECEPTOR 1B | Uniprot Protein Name |
HTR1B | Uniprot Gene Name |
Interpro Type | Family |
Interpro Acc | IPR000276 |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
PA29549 | PharmGKB ID |
HTR1DB | GENE_SYMBOL |
HTR1B | GENE_SYMBOL |
5-hydroxytryptamine receptor 1B | UNIPROT |
ENSG00000135312 | Gene Symbol |
HTR1B | Ensembl Id |
DRUGGABLE GENOME |
3351 | Gene ID |
5-HT1B | dGene Synonym |
5-HT1DB | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
HTR1B | TTD Gene Abbreviation |
T07806 | TTD Target ID |