DGIdb - IL13 Gene Record

IL13 3596 Druggable Genome

Alternate Names:

3596

INTERLEUKIN 13

IL13

IL-13

P600

147683

5973

ENSG00000169194

OTTHUMG00000059723

P35225

NC30

Interleukin-13

PA199

T29143

Gene Info:

Target Class Miscellaneous

Target Subclass Ligand

Target Subclass Cytokine

Gene Biotype PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

EXTERNAL SIDE OF PLASMA MEMBRANE

DRUGGABLE GENOME

Publications:

Diekstra MH et al., 2015, Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma., Eur J Clin Pharmacol

LEBRIKIZUMAB IL13

Interaction Score: 15.46

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
QAX-576 IL13

Interaction Score: 15.46

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
ANRUKINZUMAB IL13

Interaction Score: 15.46

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
TRALOKINUMAB IL13

Interaction Score: 11.59

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

Trial Name CAT-354

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions TTD
CNTO-5825 IL13

Interaction Score: 7.73

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
TNX-650 IL13

Interaction Score: 7.73

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name TNX-650

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
ROMILKIMAB IL13

Interaction Score: 2.58

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
SUNITINIB IL13

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26387812

Sources:
PharmGKB

Ensembl: ENSG00000169194
- Version: 101_38
Alternate Names:

IL13 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TdgClinicalTrial: P35225
- Version: January-2014
Alternate Names:

IL13 Gene Symbol

Gene Info:

Target Class Miscellaneous

Target Subclass Ligand

Target Subclass Cytokine

Publications:

PharmGKB: IL13

Version: 18-August-2020

Alternate Names:

PA199 PharmGKB ID

Gene Info:

Publications:

Diekstra MH et al., 2015, Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma., Eur J Clin Pharmacol

Chen J et al., 2011, Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine., Vaccine

HingoraniCasas: ENSG00000169194
- Version: 31-May-2017
Alternate Names:

ENSG00000169194 Gene Symbol

IL13 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
ChemblInteractions: NC30
- Version: chembl_23
Alternate Names:

NC30 GENE_SYMBOL

IL13 GENE_SYMBOL

Interleukin-13 UNIPROT

Gene Info:

Publications:
GO: IL13
- Version: 01-February-2022
Alternate Names:

NC30 GO Gene Synonym

Gene Info:

Gene Categories:

EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:
TTD: Interleukin-13
- Version: 2020.06.01
Alternate Names:

IL13 TTD Gene Abbreviation

T29143 TTD Target ID

Gene Info:

Publications:

Target Class	Miscellaneous
Target Subclass	Ligand
Target Subclass	Cytokine
Gene Biotype	PROTEIN_CODING

Mechanism of Interaction	Interleukin-13 inhibitor
Direct Interaction	yes

3596
INTERLEUKIN 13
IL13
IL-13
P600
147683
5973
ENSG00000169194
OTTHUMG00000059723
P35225
NC30
Interleukin-13
PA199
T29143

EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME

Trial Name	TNX-650
Novel drug target	Novel Target

ENSG00000169194	Gene Symbol
IL13	Ensembl Id

IL13 Gene Record

IL13 3596 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Interleukin-13 inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Interleukin-13 inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Interleukin-13 inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Interleukin-13 inhibitor Direct Interaction yes Trial Name CAT-354

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info: Trial Name TNX-650 Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26387812

Sources: PharmGKB

Ensembl: ENSG00000169194

Alternate Names: IL13 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

TdgClinicalTrial: P35225

Alternate Names: IL13 Gene Symbol

Gene Info: Target Class Miscellaneous Target Subclass Ligand Target Subclass Cytokine

Publications:

PharmGKB: IL13

Alternate Names: PA199 PharmGKB ID

Gene Info:

HingoraniCasas: ENSG00000169194

Alternate Names: ENSG00000169194 Gene Symbol IL13 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

ChemblInteractions: NC30

Alternate Names: NC30 GENE_SYMBOL IL13 GENE_SYMBOL Interleukin-13 UNIPROT

Gene Info:

Publications:

GO: IL13

Alternate Names: NC30 GO Gene Synonym

Gene Info:

Gene Categories: EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

TTD: Interleukin-13

Alternate Names: IL13 TTD Gene Abbreviation T29143 TTD Target ID

Gene Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Interleukin-13 inhibitor

Direct Interaction yes

Trial Name CAT-354

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name TNX-650

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
26387812

Sources:
PharmGKB

Alternate Names:

IL13 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

IL13 Gene Symbol

Gene Info:

Target Class Miscellaneous

Target Subclass Ligand

Target Subclass Cytokine

Alternate Names:

PA199 PharmGKB ID

Alternate Names:

ENSG00000169194 Gene Symbol

IL13 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

NC30 GENE_SYMBOL

IL13 GENE_SYMBOL

Interleukin-13 UNIPROT

Alternate Names:

NC30 GO Gene Synonym

Gene Categories:

EXTERNAL SIDE OF PLASMA MEMBRANE

Alternate Names:

IL13 TTD Gene Abbreviation

T29143 TTD Target ID