IL23A Gene Record

  • IL23A 51561 Druggable Genome

    Alternate Names:

    51561
    INTERLEUKIN 23 SUBUNIT ALPHA
    IL23A
    IL-23
    IL-23A
    IL23P19
    P19
    SGRF
    605580
    15488
    ENSG00000110944
    OTTHUMG00000187402
    Q9NPF7
    IL23A_HUMAN
    INTERLEUKIN-23
    IL-23 subunit alpha
    Interleukin-23 subunit p19
    IL-23-A
    IL-23p19
    Interleukin-23 subunit alpha
    PA29824
    T06841
    IL23

    Gene Info:

    Target Class Receptors
    Target Subclass Receptor
    Target Subclass Type 1 cytokine receptor
    Target Class Miscellaneous
    Target Class Other
    Target Main Class Other
    Target Subclass Ligand
    Target Subclass Cytokine
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • GUSELKUMAB   IL23A

    Interaction Score: 30.91

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Interleukin-23 subunit alpha inhibitor
    Direct Interaction yes

    PMIDs:
    26714681


    Sources:
    ChemblInteractions TTD

  • BRAZIKUMAB   IL23A

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • RISANKIZUMAB   IL23A

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • TILDRAKIZUMAB   IL23A

    Interaction Score: 10.3

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Interleukin-23 subunit alpha inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • BRIAKINUMAB   IL23A

    Interaction Score: 6.87

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name Briakinumab
    Novel drug target Established target
    Mechanism of Interaction Interleukin-23 inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • USTEKINUMAB   IL23A

    Interaction Score: 6.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name -
    Mechanism of Interaction Interleukin-23 inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TEND PharmGKB TTD FDA

  • Ensembl: ENSG00000110944

    • Version: 101_38

    Alternate Names:
    IL23A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: Q9NPF7

    • Version: January-2014

    Alternate Names:
    IL23A Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptor
    Target Subclass Type 1 cytokine receptor

    Publications:

  • TEND: Q9NPF7

    • Version: 01-August-2011

    Alternate Names:
    ENSG00000110944 Ensembl Gene Id
    IL23A Gene Symbol
    51561 Entrez Gene Id

    Gene Info:
    Target Main Class Other
    Target Subclass Ligand
    Target Subclass Cytokine

    Publications:

  • HingoraniCasas: ENSG00000110944

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000110944 Gene Symbol
    IL23A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: SGRF

    • Version: chembl_23

    Alternate Names:
    SGRF GENE_SYMBOL
    IL23A GENE_SYMBOL
    Interleukin-23 subunit alpha UNIPROT

    Gene Info:

    Publications:

  • PharmGKB: IL23A

    • Version: 18-August-2020

    Alternate Names:
    PA29824 PharmGKB ID

    Gene Info:

    Publications:

  • TTD: Interleukin-23

    • Version: 2020.06.01

    Alternate Names:
    IL23 TTD Gene Abbreviation
    T06841 TTD Target ID

    Gene Info:

    Publications:

  • FDA: IL23A

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Publications: