3559 |
INTERLEUKIN 2 RECEPTOR SUBUNIT ALPHA |
IL2RA |
CD25 |
IDDM10 |
IL2R |
IMD41 |
TCGFR |
p55 |
147730 |
6008 |
ENSG00000134460 |
OTTHUMG00000017616 |
P01589 |
IL2RA_HUMAN |
IL-2 receptor subunit alpha |
CD_antigen=CD25 |
TAC antigen |
Interleukin-2 receptor subunit alpha |
IL-2R subunit alpha |
IL-2-RA |
IL2-RA |
P42701 |
IL12RB1 |
PA29828 |
Interleukin 2 receptor |
T20710 |
Interleukin 2 receptor alpha |
T03313 |
Target Class | Receptors |
Target Subclass | Receptor |
Target Subclass | Type 1 cytokine receptor |
Target Subclass | CytokineR |
Target Main Class | Receptors |
Transmembrane Helix Count | 1 |
Target Subclass | IG |
Target Subclass | Type1 |
Gene Biotype | PROTEIN_CODING |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
antibody (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Interleukin-2 receptor inhibitor |
Direct Interaction | yes |
Trial Name | basiliximab,Simulect |
agonist (activating) |
modulator |
Novel drug target | Established target |
Trial Name | Proleukin IL-2 |
Mechanism of Interaction | Interleukin-2 receptor agonist |
antibody (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Interleukin-2 receptor inhibitor |
Direct Interaction | yes |
Novel drug target | Established target |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | Interleukin-2 receptor alpha chain binding agent |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Interleukin-2 receptor alpha chain antagonist |
agonist (activating) |
Trial Name | IRX-2 |
Novel drug target | Established target |
IL2RA | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
IL12RB1 | Gene Symbol |
IL2RA | Gene Symbol |
Target Class | Receptors |
Target Subclass | Receptor |
Target Subclass | Type 1 cytokine receptor |
P01589 | Uniprot Accession |
3559 | Entrez Gene Id |
IL2RA | Gene Symbol |
Target Subclass | CytokineR |
Target Main Class | Receptors |
Transmembrane Helix Count | 1 |
IL2RA | Gene Symbol |
Target Class | Receptors |
Target Subclass | Receptor |
Target Subclass | Type 1 cytokine receptor |
p55 | UNIPROT |
IL2RA | GENE_SYMBOL |
Interleukin-2 receptor subunit alpha | UNIPROT |
ENSG00000134460 | Gene Symbol |
IL2RA | Ensembl Id |
DRUGGABLE GENOME |
PA29828 | PharmGKB ID |
IL2RA | Gene Symbol |
CLINICALLY ACTIONABLE |
IL2R | TTD Gene Abbreviation |
T20710 | TTD Target ID |
IL2RA | TTD Gene Abbreviation |
T03313 | TTD Target ID |
EXTERNAL SIDE OF PLASMA MEMBRANE |