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IMPDH1 3614 Druggable Genome
Alternate Names:
3614 INOSINE MONOPHOSPHATE DEHYDROGENASE 1 IMPDH1 IMPD IMPD1 IMPDH-I LCA11 RP10 sWSS2608 146690 6052 ENSG00000106348 OTTHUMG00000157713 IMPD 1 IMP DEHYDROGENASE 1 INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 P20839 IMPDH 1 IMDH1_HUMAN INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 (EC 1.1.1.205) (IMP DEHYDROGENASE 1) (IMPDH-I) (IMPD 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P20839] PA29862 T40111 Gene Info:
Target Class Enzymes Target Subclass EC:1.1.1.205 Interpro Name IMP dehydrogenase/GMP reductase Uniprot Status Swiss-Prot Human Readable Name DRUGGABLE GENOME Uniprot Evidence 1: Evidence at protein level Interpro Short Name IMP_DH_GMPRt Interpro Acc IPR001093 Interpro Type Domain Target Subclass 1.1.1.205 Target Main Class Enzymes Gene Biotype PROTEIN_CODING Gene Categories: Category Details
DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 6.18
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Interaction Score: 6.18
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Interaction Score: 3.09
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor Direct Interaction yes -
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name AVN-944 Novel drug target Established target -
Interaction Score: 3.09
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Interaction Score: 1.03
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor Direct Interaction yes -
Interaction Score: 0.77
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor -
Interaction Score: 0.52
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Interaction Score: 0.24
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor Direct Interaction yes
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- Version: 101_38
Alternate Names:
IMPDH1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
ENSG00000106348 Ensembl Gene Id IMDH1_HUMAN Uniprot Id P20839 Uniprot Accession Gene Info:
Target Subclass 1.1.1.205 Target Main Class Enzymes Publications:
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- Version: January-2014
Alternate Names:
IMPDH1 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:1.1.1.205 Publications:
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- Version: 11-September-2012
Alternate Names:
ENSG00000106348 Ensembl Gene Id INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 Uniprot Protein Name IMDH1_HUMAN Uniprot Id Gene Info:
Interpro Name IMP dehydrogenase/GMP reductase Uniprot Status Swiss-Prot Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 (EC 1.1.1.205) (IMP DEHYDROGENASE 1) (IMPDH-I) (IMPD 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P20839] Description IMPDH1 Display Id ENSG00000106348 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
PA29862 PharmGKB ID Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000106348 Gene Symbol IMPDH1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
IMPD1 GENE_SYMBOL IMPDH1 GENE_SYMBOL Inosine-5'-monophosphate dehydrogenase 1 UNIPROT Gene Info:
Publications:
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- Version: 2020.06.01
Alternate Names:
IMPDH1 TTD Gene Abbreviation T40111 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Inosine-5'-monophosphate dehydrogenase 1 Gene Name P20839 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: