-
ITGA4 3676 Druggable Genome
Alternate Names:
3676 INTEGRIN SUBUNIT ALPHA 4 ITGA4 CD49D IA4 192975 6140 ENSG00000115232 OTTHUMG00000154212 P13612 INTEGRIN ALPHA-4 INTEGRIN ALPHA-IV INTEGRIN ALPHA-4 PRECURSOR (INTEGRIN ALPHA-IV) (VLA-4) (CD49D). [SOURCE:UNIPROT/SWISSPROT;ACC:P13612] CD_antigen=CD49d VLA-4 subunit alpha CD49 antigen-like family member D ITA4_HUMAN T97587 Gene Info:
Human Readable Name DRUGGABLE GENOME Target Class Receptors Target Subclass Receptors Target Subclass Integrin Target Main Class Receptors Target Subclass Other_receptors Transmembrane Helix Count 1 Interpro Acc IPR000413 Interpro Short Name Integrin_alpha Interpro Name Integrin alpha chain Interpro Type Family Uniprot Status Swiss-Prot Uniprot Evidence 1: Evidence at protein level Gene Biotype PROTEIN_CODING Gene Categories: Category Details
CELL SURFACE EXTERNAL SIDE OF PLASMA MEMBRANE DRUGGABLE GENOME Publications:
-
Interaction Score: 27.48
Interaction Types & Directionality:
antibody (inhibitory) inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name natalizumab ,Tysabri Mechanism of Interaction Integrin alpha-4/beta-7 inhibitor
Sources:
TdgClinicalTrial ChemblInteractions TEND -
Interaction Score: 15.46
Interaction Types & Directionality:
antibody (inhibitory) inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name vedolizumab, MLN-02 Direct Interaction yes -
Interaction Score: 10.3
-
Interaction Score: 6.87
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name SB-683699, T-0047 Direct Interaction yes
-
- Version: 101_38
Alternate Names:
ITGA4 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 11-September-2012
Alternate Names:
ITGA4 Uniprot Gene Name ENSG00000115232 Ensembl Gene Id 3676 Entrez Gene Id Gene Info:
Interpro Acc IPR000413 Interpro Short Name Integrin_alpha Interpro Name Integrin alpha chain Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
ENSG00000115232 Ensembl Gene Id P13612 Uniprot Accession 3676 Entrez Gene Id Gene Info:
Target Subclass Integrin Target Main Class Receptors Target Subclass Other_receptors Publications:
-
- Version: 26-July-2011
Alternate Names:
ENSG00000115232 Ensembl Gene Id INTEGRIN ALPHA-4 PRECURSOR (INTEGRIN ALPHA-IV) (VLA-4) (CD49D). [SOURCE:UNIPROT/SWISSPROT;ACC:P13612] Description ITGA4 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: January-2014
Alternate Names:
ITGA4 Gene Symbol Gene Info:
Target Class Receptors Target Subclass Receptors Target Subclass Integrin Publications:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000115232 Gene Symbol ITGA4 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
CD49D GENE_SYMBOL ITGA4 GENE_SYMBOL Integrin alpha-4 UNIPROT Gene Info:
Publications:
-
Alternate Names:
CD49D GO Gene Synonym Gene Info:
Gene Categories:
CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE Publications:
-
- Version: 2020.06.01
Alternate Names:
ITGA4 TTD Gene Abbreviation T97587 TTD Target ID Gene Info:
Publications: