• ITGB6 3694 Druggable Genome

    Alternate Names:

    3694
    INTEGRIN SUBUNIT BETA 6
    ITGB6
    AI1H
    147558
    6161
    ENSG00000115221
    OTTHUMG00000132026
    Integrin beta-6
    INTEGRIN BETA-6 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18564]
    ITB6_HUMAN
    P18564

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Integrin_bsu_N
    Interpro Type Domain
    Interpro Acc IPR002369
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Integrin beta subunit, N-terminal
    Target Class Miscellaneous
    Target Subclass Receptor
    Target Subclass integrin
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 7.73

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-6 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Integrin alpha-V/beta-6 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.09

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Integrin alpha-V/beta-6 antagonist

    PMIDs:
    None found


  • Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name GLPG0187
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

    • Version: 101_38

    Alternate Names:
    ITGB6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    INTEGRIN BETA-6 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18564] Description
    ITGB6 Display Id
    ENSG00000115221 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    ITGB6 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Receptor
    Target Subclass integrin

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ITGB6 Uniprot Gene Name
    ENSG00000115221 Ensembl Gene Id
    ITB6_HUMAN Uniprot Id

    Gene Info:
    Interpro Short Name Integrin_bsu_N
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000115221 Gene Symbol
    ITGB6 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    ITGB6 GENE_SYMBOL
    Integrin beta-6 UNIPROT

    Gene Info:

    Publications:

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications: