3695 |
INTEGRIN SUBUNIT BETA 7 |
ITGB7 |
147559 |
6162 |
ENSG00000139626 |
OTTHUMG00000169775 |
INTEGRIN BETA-7 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P26010] |
P26010 |
ITB7_HUMAN |
INTEGRIN BETA-7 |
Gut homing receptor beta subunit |
T14065 |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Receptors |
Target Subclass | Receptors |
Target Subclass | Integrin |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR002369 |
Interpro Type | Domain |
Interpro Name | Integrin beta subunit, N-terminal |
Interpro Short Name | Integrin_bsu_N |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
DRUGGABLE GENOME |
antibody (inhibitory) |
inhibitor (inhibitory) |
Novel drug target | Novel Target |
Trial Name | vedolizumab, MLN-02 |
Mechanism of Interaction | Integrin alpha-4/beta-7 inhibitor |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Integrin beta-7 antagonist |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Integrin alpha-4/beta-7 inhibitor |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Integrin alpha-4/beta-7 antagonist |
ITGB7 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ENSG00000139626 | Ensembl Gene Id |
INTEGRIN BETA-7 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P26010] | Description |
ITGB7 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ITGB7 | Uniprot Gene Name |
ITB7_HUMAN | Uniprot Id |
P26010 | Uniprot Accession |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Acc | IPR002369 |
DRUGGABLE GENOME |
ITGB7 | Gene Symbol |
Target Class | Receptors |
Target Subclass | Receptors |
Target Subclass | Integrin |
ENSG00000139626 | Gene Symbol |
ITGB7 | Ensembl Id |
DRUGGABLE GENOME |
ITGB7 | GENE_SYMBOL |
Integrin beta-7 | UNIPROT |
Gut homing receptor beta subunit | UNIPROT |
ITGB7 | TTD Gene Abbreviation |
T14065 | TTD Target ID |
CELL SURFACE |