KCNQ4 Gene Record

  • EZOGABINE   KCNQ4

    Interaction Score: 8.83

    Interaction Types & Directionality:
    activator (activating)
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction KCNQ (Kv7) potassium channel blocker
    Direct Interaction yes
    Trial Name retigabine, ezogabine,Potiga

    PMIDs:
    11378159 16713428 17184917


    Sources:
    TdgClinicalTrial ChemblInteractions

  • FLINDOKALNER   KCNQ4

    Interaction Score: 1.77

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel subunit Kv7.4 activator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CELECOXIB   KCNQ4

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22336956


    Sources:
    PharmGKB

  • TEDISAMIL   KCNQ4

    Interaction Score: 0.23

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GUANIDINE HYDROCHLORIDE   KCNQ4

    Interaction Score: 0.23

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DALFAMPRIDINE   KCNQ4

    Interaction Score: 0.21

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • NERISPIRDINE   KCNQ4

    Interaction Score: 0.18

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000117013

    • Version: 101_38

    Alternate Names:
    KCNQ4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000117013

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000117013 Ensembl Gene Id
    POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 (VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KV7.4) (POTASSIUM CHANNEL ALPHA SUBUNIT KVLQT4) (KQT-LIKE 4). [SOURCE:UNIPROT/SWISSPROT;ACC:P56696] Description
    KCNQ4 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • BaderLabGenes: KCNQ4

    • Version: February-2014

    Alternate Names:
    9132 Entrez Gene ID

    Gene Info:
    Initial Gene Query Kv7.4
    Counted Citations from 1950-2000 136

    Gene Categories:
    ION CHANNEL

    Publications:

  • HopkinsGroom: P56696

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000117013 Ensembl Gene Id
    KCNQ4_HUMAN Uniprot Id
    9132 Entrez Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Name Ion transport domain
    Human Readable Name ION CHANNEL

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P56696

    • Version: January-2014

    Alternate Names:
    KCNQ4 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC.1.A.1.15.4

    Publications:

  • PharmGKB: KCNQ4

    • Version: 18-August-2020

    Alternate Names:
    PA30076 PharmGKB ID

    Gene Info:

    Publications:
    Gong L et al., 2012, Celecoxib pathways: pharmacokinetics and pharmacodynamics., Pharmacogenet Genomics

  • HingoraniCasas: ENSG00000117013

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000117013 Gene Symbol
    KCNQ4 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: KCNQ4

    • Version: chembl_23

    Alternate Names:
    KCNQ4 GENE_SYMBOL
    Potassium voltage-gated channel subfamily KQT member 4 UNIPROT
    KQT-like 4 UNIPROT

    Gene Info:

    Publications:

  • HumanProteinAtlas: KCNQ4

    • Version: 19.3

    Alternate Names:
    ENSG00000117013 Ensembl Gene ID
    DFNA2 Human Protein Atlas Gene Synonym
    Kv7.4 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER, ION CHANNEL

    Publications:

  • Pharos: KCNQ4

    • Version: 01-February-2022

    Alternate Names:
    Potassium voltage-gated channel subfamily KQT member 4 Gene Name
    P56696 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: