LHCGR Gene Record

  • MENOTROPINS   LHCGR

    Interaction Score: 18.03

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Novel drug target Established target
    Trial Name -
    Mechanism of Interaction Luteinizing hormone/Choriogonadotropin receptor agonist

    PMIDs:
    14680547 7872378 17016423 17139284


    Sources:
    TdgClinicalTrial ChemblInteractions TEND

  • CHEMBL448753   LHCGR

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19296599


    Sources:
    DTC

  • LUTROPIN ALFA   LHCGR

    Interaction Score: 5.15

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Luteinizing hormone/Choriogonadotropin receptor agonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • LH (MENOTROPINS)   LHCGR

    Interaction Score: 5.15

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Luteinizing hormone/Choriogonadotropin receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GONADOTROPIN, CHORIONIC   LHCGR

    Interaction Score: 5.15

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Luteinizing hormone/Choriogonadotropin receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AVICINE   LHCGR

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name CTP-37,Avicine

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • CHORIOGONADOTROPIN ALFA   LHCGR

    Interaction Score: 5.15

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Luteinizing hormone/Choriogonadotropin receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GOSERELIN   LHCGR

    Interaction Score: 4.29

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    20053189 17016423 17139284


    Sources:
    TdgClinicalTrial TEND

  • GTX-758   LHCGR

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name GTx-758
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • RELUGOLIX   LHCGR

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CHEMBL505670   LHCGR

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL429095   LHCGR

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000138039

    • Version: 101_38

    Alternate Names:
    LHCGR Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P22888

    • Version: 11-September-2012

    Alternate Names:
    P22888 Uniprot Accession
    3973 Entrez Gene Id
    LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR Uniprot Protein Name

    Gene Info:
    Interpro Name GPCR, rhodopsin-like, 7TM
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR000276

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000138039

    • Version: 26-July-2011

    Alternate Names:
    LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR PRECURSOR (LH/CG-R) (LSH- R) (LUTEINIZING HORMONE RECEPTOR) (LHR). [SOURCE:UNIPROT/SWISSPROT;ACC:P22888] Description
    ENSG00000138039 Ensembl Gene Id
    LHCGR Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P22888

    • Version: January-2014

    Alternate Names:
    LHCGR Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

  • TEND: P22888

    • Version: 01-August-2011

    Alternate Names:
    P22888 Uniprot Accession
    LHCGR Gene Symbol
    LSHR_HUMAN Uniprot Id

    Gene Info:
    Target Subclass GPCR
    Target Main Class Receptors
    Target Subclass Rhodopsin

    Publications:

  • DTC: LHCGR

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Heitman LH et al., 2009, Substituted terphenyl compounds as the first class of low molecular weight allosteric inhibitors of the luteinizing hormone receptor., J Med Chem

  • HingoraniCasas: ENSG00000138039

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000138039 Gene Symbol
    LHCGR Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: LCGR

    • Version: chembl_23

    Alternate Names:
    LGR2 GENE_SYMBOL
    LHRHR GENE_SYMBOL
    LHCGR GENE_SYMBOL

    Gene Info:

    Publications:

  • dGene: LHCGR

    • Version: 27-Jun-2013

    Alternate Names:
    3973 Gene ID
    HHG dGene Synonym
    LCGR dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • TTD: Luteinizing hormone receptor

    • Version: 2020.06.01

    Alternate Names:
    LHCGR TTD Gene Abbreviation
    T79473 TTD Target ID

    Gene Info:

    Publications: