4129 |
MONOAMINE OXIDASE B |
MAOB |
309860 |
6834 |
ENSG00000069535 |
OTTHUMG00000021388 |
P27338 |
MA0B |
AMINE OXIDASE [FLAVIN-CONTAINING] B (EC 1.4.3.4) (MONOAMINE OXIDASE TYPE B) (MAO-B). [SOURCE:UNIPROT/SWISSPROT;ACC:P27338] |
AOFB_HUMAN |
Monoamine oxidase type B |
MAO-B |
Amine oxidase [flavin-containing] B |
T83011 |
Target Class | Enzymes |
Target Subclass | EC:1.4.3 |
Target Subclass | EC:1.4.3.4 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Acc | IPR002937 |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | Amine oxidase |
Interpro Short Name | Amino_oxidase |
Uniprot Status | Swiss-Prot |
Target Main Class | Enzymes |
Transmembrane Helix Count | 1 |
Target Subclass | 1.4.3 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
ENZYME |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
Direct Interaction | yes |
Trial Name | selegiline transdermal,Emsam |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Monoamine oxidase inhibitor |
Trial Name | - |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
Direct Interaction | yes |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Trial Name | Safinamide |
Novel drug target | Established target |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Monoamine oxidase inhibitor |
n/a |
Trial Name | V3381 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | low dose intravenous methamphetamine |
inhibitor (inhibitory) |
Mechanism of Interaction | Monoamine oxidase B inhibitor |
Direct Interaction | yes |
MAOB | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
MA0B | Gene Symbol |
MAOB | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:1.4.3 |
Target Subclass | EC:1.4.3.4 |
MAOB | Uniprot Gene Name |
P27338 | Uniprot Accession |
4129 | Entrez Gene Id |
Interpro Type | Domain |
Interpro Acc | IPR002937 |
Uniprot Evidence | 1: Evidence at protein level |
DRUGGABLE GENOME |
4129 | Entrez Gene Id |
P27338 | Uniprot Accession |
MAOB | Gene Symbol |
Target Main Class | Enzymes |
Transmembrane Helix Count | 1 |
Target Subclass | 1.4.3 |
AMINE OXIDASE [FLAVIN-CONTAINING] B (EC 1.4.3.4) (MONOAMINE OXIDASE TYPE B) (MAO-B). [SOURCE:UNIPROT/SWISSPROT;ACC:P27338] | Description |
ENSG00000069535 | Ensembl Gene Id |
MAOB | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
MAOB | GENE_SYMBOL |
Amine oxidase [flavin-containing] B | UNIPROT |
Monoamine oxidase type B | UNIPROT |
ENSG00000069535 | Gene Symbol |
MAOB | Ensembl Id |
DRUGGABLE GENOME |
MAO-B | TTD Gene Abbreviation |
T83011 | TTD Target ID |
Amine oxidase [flavin-containing] B | Gene Name |
P27338 | UniProt ID |
ENZYME |