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MAP2K4 6416 Druggable GenomeClinically Actionable
Alternate Names:
6416 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 MAP2K4 JNKK JNKK1 MAPKK4 MEK4 MKK4 PRKMK4 SAPKK-1 SAPKK1 SEK1 SERK1 SKK1 601335 6844 ENSG00000065559 OTTHUMG00000178267 P45985 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 MP2K4_HUMAN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 (EC 2.7.1.37) (EC 2.7.1.112) (MAP KINASE KINASE 4) (JNK ACTIVATING KINASE 1) (C-JUN N-TERMINAL KINASE KINASE 1) (JNKK) (SAPK/ERK KINASE 1) (SEK1). [SOURCE:UNIPROT/SWISSPROT;ACC:P45985] PA30589 Gene Info:
Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Interpro Type Domain Human Readable Name KINASE Interpro Acc IPR002290 Interpro Short Name Ser/Thr_dual-sp_kinase_dom Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain Target Class Enzymes Target Subclass EC:2.7.12.2 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE SERINE THREONINE KINASE TYROSINE KINASE DRUGGABLE GENOME CLINICALLY ACTIONABLE Publications:
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Interaction Types & Directionality:
n/a Interaction Info:
Trial Name WX-554 Novel drug target Novel Target -
Interaction Score: 0.74
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
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Interaction Score: 0.57
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
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Interaction Score: 0.29
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
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Interaction Score: 0.25
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
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- Version: 101_38
Alternate Names:
MAP2K4 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
MAP2K4 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:2.7.12.2 Publications:
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- Version: 26-July-2011
Alternate Names:
DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 (EC 2.7.1.37) (EC 2.7.1.112) (MAP KINASE KINASE 4) (JNK ACTIVATING KINASE 1) (C-JUN N-TERMINAL KINASE KINASE 1) (JNKK) (SAPK/ERK KINASE 1) (SEK1). [SOURCE:UNIPROT/SWISSPROT;ACC:P45985] Description ENSG00000065559 Ensembl Gene Id MAP2K4 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
ENSG00000065559 Ensembl Gene Id MP2K4_HUMAN Uniprot Id P45985 Uniprot Accession Gene Info:
Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000065559 Gene Symbol MAP2K4 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
PA30589 PharmGKB ID Gene Info:
Publications:
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Alternate Names:
JNKK1 GO Gene Synonym MEK4 GO Gene Synonym MKK4 GO Gene Synonym Gene Info:
Gene Categories:
SERINE THREONINE KINASE, TYROSINE KINASE Publications:
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Alternate Names:
MAP2K4 Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
6416 Gene ID JNKK dGene Synonym JNKK1 dGene Synonym Gene Info:
Gene Categories:
KINASE, SERINE THREONINE KINASE Publications:
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Alternate Names:
Dual specificity mitogen-activated protein kinase kinase 4 Gene Name P45985 UniProt ID Gene Info:
Gene Categories:
KINASE Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 30-February-2014
Alternate Names:
Gene Info:
Publications:
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- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 04-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: