MME Gene Record

  • CANDOXATRIL   MME

    Interaction Score: 34.78

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name -

    PMIDs:
    16025254 1315825 11752352 16449355 1386491 7511759


    Sources:
    TdgClinicalTrial TEND TTD

  • SACUBITRIL   MME

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Neprilysin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SAMPATRILAT   MME

    Interaction Score: 7.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • LCZ696   MME

    Interaction Score: 7.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • ILEPATRIL   MME

    Interaction Score: 3.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name ilepatril, AVE-7688
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • SLV-334   MME

    Interaction Score: 3.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • PEPINEMAB   MME

    Interaction Score: 3.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • GALLOPAMIL   MME

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Ensembl: ENSG00000196549

    • Version: 101_38

    Alternate Names:
    MME Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000196549

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000196549 Ensembl Gene Id
    MME Display Id
    NEPRILYSIN (EC 3.4.24.11) (NEUTRAL ENDOPEPTIDASE) (NEP) (ENKEPHALINASE) (COMMON ACUTE LYMPHOCYTIC LEUKEMIA ANTIGEN) (CALLA) (NEUTRAL ENDOPEPTIDASE 24.11) (CD10). [SOURCE:UNIPROT/SWISSPROT;ACC:P08473] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TEND: P08473

    • Version: 01-August-2011

    Alternate Names:
    NEP_HUMAN Uniprot Id
    MME Gene Symbol
    P08473 Uniprot Accession

    Gene Info:
    Transmembrane Helix Count 1
    Target Main Class Enzymes
    Target Subclass 3.4.24

    Publications:

  • TdgClinicalTrial: P08473

    • Version: January-2014

    Alternate Names:
    MME Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.24

    Publications:

  • PharmGKB: MME

    • Version: 18-August-2020

    Alternate Names:
    PA30864 PharmGKB ID

    Gene Info:

    Publications:
    Grilo A et al., 2011, Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough., Pharmacogenet Genomics

  • HingoraniCasas: ENSG00000196549

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000196549 Gene Symbol
    MME Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: EPN

    • Version: chembl_23

    Alternate Names:
    EPN GENE_SYMBOL
    MME GENE_SYMBOL
    Neprilysin UNIPROT

    Gene Info:

    Publications:

  • GO: MME

    • Version: 01-February-2022

    Alternate Names:
    EPN GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

  • dGene: MME

    • Version: 27-Jun-2013

    Alternate Names:
    4311 Gene ID
    CALLA dGene Synonym
    CD10 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • TTD: Neutral endopeptidase

    • Version: 2020.06.01

    Alternate Names:
    MME TTD Gene Abbreviation
    T05409 TTD Target ID

    Gene Info:

    Publications: