4547 |
MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN |
MTTP |
ABL |
MTP |
157147 |
7467 |
ENSG00000138823 |
OTTHUMG00000131023 |
P55157 |
MTP_HUMAN |
Microsomal triglyceride transfer protein large subunit |
MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P55157] |
PA164742099 |
T46628 |
Target Class | Transporters |
Target Subclass | Miscellaneous |
Target Subclass | Lipid_transp |
Human Readable Name | DRUGGABLE GENOME |
Interpro Short Name | Lipid_transpt_N |
Interpro Acc | IPR001747 |
Interpro Name | Lipid transport protein, N-terminal |
Uniprot Status | Swiss-Prot |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Trial Name | SLx-4090 |
Novel drug target | Novel Target |
n/a |
Trial Name | implitapide, AEGR427 |
Novel drug target | Novel Target |
inhibitor (inhibitory) |
Mechanism of Interaction | Microsomal triglyceride transfer protein inhibitor |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | lomitapide , AEGR-733, BMS-201038 |
Novel drug target | Novel Target |
MTTP | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P55157] | Description |
MTP | Display Id |
ENSG00000138823 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
4547 | Entrez Gene Id |
P55157 | Uniprot Accession |
MTTP | Uniprot Gene Name |
Interpro Short Name | Lipid_transpt_N |
Interpro Acc | IPR001747 |
Interpro Name | Lipid transport protein, N-terminal |
DRUGGABLE GENOME |
MTTP | Gene Symbol |
Target Class | Transporters |
Target Subclass | Miscellaneous |
Target Subclass | Lipid_transp |
PA164742099 | PharmGKB ID |
ENSG00000138823 | Gene Symbol |
MTTP | Ensembl Id |
DRUGGABLE GENOME |
MTP | GENE_SYMBOL |
MTTP | GENE_SYMBOL |
Microsomal triglyceride transfer protein large subunit | UNIPROT |
MTTP | TTD Gene Abbreviation |
T46628 | TTD Target ID |