MYLK Gene Record

  • MYLK 4638 Druggable Genome

    Alternate Names:

    4638
    MYOSIN LIGHT CHAIN KINASE
    MYLK
    AAT7
    KRP
    MLCK
    MLCK1
    MLCK108
    MLCK210
    MSTP083
    MYLK1
    smMLCK
    600922
    7590
    ENSG00000065534
    OTTHUMG00000141304
    Q15746
    MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE AND NON-MUSCLE ISOZYMES (EC 2.7.1.117) (MLCK) [CONTAINS: TELOKIN (KINASE RELATED PROTEIN) (KRP)]. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15746]
    MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE, DEGLUTAMYLATED FORM
    MYLK_HUMAN
    Myosin light kinase
    T97141
    MMIHS
    MMIHS1
    Myosin light chain kinase, smooth muscle

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • TOZASERTIB   MYLK

    Interaction Score: 1.77

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • Ensembl: ENSG00000065534

    • Version: 101_38

    Alternate Names:
    MYLK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q15746

    • Version: 11-September-2012

    Alternate Names:
    MYLK_HUMAN Uniprot Id
    MYLK Uniprot Gene Name
    Q15746 Uniprot Accession

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000065534

    • Version: 26-July-2011

    Alternate Names:
    MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE AND NON-MUSCLE ISOZYMES (EC 2.7.1.117) (MLCK) [CONTAINS: TELOKIN (KINASE RELATED PROTEIN) (KRP)]. [SOURCE:UNIPROT/SWISSPROT;ACC:Q15746] Description
    MYLK Display Id
    ENSG00000065534 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: MYLK

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

  • HingoraniCasas: ENSG00000065534

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000065534 Gene Symbol
    MYLK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: MYLK

    • Version: 19.3

    Alternate Names:
    ENSG00000065534 Ensembl Gene ID
    MLCK Human Protein Atlas Gene Synonym
    MLCK1 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • dGene: MYLK

    • Version: 27-Jun-2013

    Alternate Names:
    4638 Gene ID
    AAT7 dGene Synonym
    KRP dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Myosin light kinase

    • Version: 2020.06.01

    Alternate Names:
    MYLK TTD Gene Abbreviation
    T97141 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: MYLK

    • Version: 01-February-2022

    Alternate Names:
    Myosin light chain kinase, smooth muscle Gene Name
    Q15746 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications: