NOTCH2 Gene Record

  • NOTCH2 4853 Druggable GenomeClinically Actionable

    Alternate Names:

    4853
    NOTCH 2
    NOTCH2
    AGS2
    HJCYS
    hN2
    600275
    7882
    ENSG00000134250
    OTTHUMG00000012177
    Notch Pathway
    Q04721
    notch receptor 2
    Notch-2 receptor
    T88656

    Gene Info:

    Target Class Receptors
    Target Subclass Receptors
    Target Subclass Notch
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE

    Publications:

  • TAREXTUMAB   NOTCH2

    Interaction Score: 20.61

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Trial Name OMP-59R5
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial TTD

  • NIROGACESTAT   NOTCH2

    Interaction Score: 4.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • RG-4733   NOTCH2

    Interaction Score: 4.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Ensembl: ENSG00000134250

    • Version: 101_38

    Alternate Names:
    NOTCH2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: Q04721

    • Version: January-2014

    Alternate Names:
    NOTCH2 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptors
    Target Subclass Notch

    Publications:

  • HingoraniCasas: ENSG00000134250

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000134250 Gene Symbol
    NOTCH2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • MyCancerGenome: NOTCH2

    • Version: 20-Jun-2017

    Alternate Names:
    4853 Entrez Gene Id
    NOTCH2 MyCancerGenome Gene Symbol
    Notch Pathway MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • Tempus: NOTCH2

    • Version: 11-November-2018

    Alternate Names:
    NOTCH2 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • TTD: Notch-2 receptor

    • Version: 2020.06.01

    Alternate Names:
    NOTCH2 TTD Gene Abbreviation
    T88656 TTD Target ID

    Gene Info:

    Publications:

  • MskImpact: NOTCH2

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • FoundationOneGenes: NOTCH2

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: NOTCH2

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • GO: NOTCH2

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

  • Oncomine: NOTCH2

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: